The phage life cycle is a multi-stage process initiated by the recognition and attachment of
the virus to its bacterial host. This adsorption step depends on the specific interaction …

Clostridium difficile, now reclassified as Clostridioides difficile, is the causative agent of C.
difficile infections (CDI). CDI is particularly challenging in healthcare settings because highly …

Bacteriophages, the most abundant organisms on earth, have the potential to address the
rise of multidrug-resistant bacteria resulting from the overuse of antibiotics. However, their …

Highlights•Surface receptor-mediated phage resistance often comes at a cost for
fitness.•Possible trade-offs may include attenuated virulence, and increased sensitivity to …

The pathogenic Clostridioides difficile and Clostridium perfringens are responsible for many
health care-associated infections as well as systemic and enteric diseases. Therefore, they …

Clostridium perfringens is a well-known pathogen that causes foodborne disease. With a
high prevalence of contamination in food, an efficient strategy is needed to decontaminate …

Phage therapy has been revitalized since antibiotic resistance in bacteria is increasing.
Compared with antibiotics, phages can target specific bacteria precisely, which requires …

Ulcerative colitis (UC) is an inflammatory bowel disease characterized by abdominal pain,
diarrhea, and rectal bleeding. This study aims to explore the protective effects of a phage …

Clostridium perfringens is an important pathogen for both humans and animals, causing
human foodborne disease and necrotic enteritis in poultry. In the present study, a C …

Escherichia coli O157: H7 is a global concern that causes serious diseases, such as
hemolytic uremic syndrome and bloody diarrhea. To control E. coli O157: H7 in food, a novel …