[HTML][HTML] On the path to predicting immune responses in the lung: modeling the pulmonary innate immune system at the air-liquid interface (ALI)

J Graf, M Trautmann-Rodriguez, S Sabnis… - European Journal of …, 2023 - Elsevier
Chronic respiratory diseases and infections are among the largest contributors to death
globally, many of which still have no cure, including chronic obstructive pulmonary disorder …

[HTML][HTML] Intestinal stromal cells in mucosal immunity and homeostasis

BMJ Owens, A Simmons - Mucosal immunology, 2013 - Elsevier
A growing body of evidence suggests that non-hematopoietic stromal cells of the intestine
have multiple roles in immune responses and inflammation at this mucosal site. Despite this …

Inflammation, innate immunity, and the intestinal stromal cell niche: opportunities and challenges

BMJ Owens - Frontiers in immunology, 2015 - frontiersin.org
Stromal cells of multiple tissues contribute to immune-mediated protective responses and,
conversely, the pathological tissue changes associated with chronic inflammatory disease …

Regulatory dendritic cells

K Sato, T Uto, T Fukaya, H Takagi - Emerging Concepts Targeting Immune …, 2017 - Springer
Dendritic cells (DCs) comprise heterogeneous subsets, functionally classified into
conventional DCs (cDCs) and plasmacytoid DCs (pDCs). DCs are considered to be …

Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis

MJW Kain, BMJ Owens - Immunology, 2013 - Wiley Online Library
Secondary lymphoid organs function to increase the efficiency of interactions between rare,
antigen‐specific lymphocytes and antigen presenting cells, concentrating antigen and …

Generation of regulatory dendritic cells after treatment with paeoniflorin

D Chen, Y Li, X Wang, K Li, Y Jing, J He, Z Qiang… - Immunologic …, 2016 - Springer
Regulatory dendritic cells are a potential therapeutic tool for assessing a variety of immune
overreaction diseases. Paeoniflorin, a bioactive glucoside extracted from the Chinese herb …

Human renal fibroblasts generate dendritic cells with a unique regulatory profile

KO Dixon, L Rossmann, SWA Kamerling… - Immunology and cell …, 2014 - Wiley Online Library
Fibroblasts reside within the renal interstitium in close proximity to neighbouring dendritic
cells (DCs). It is likely that these cells have a central role in the maintenance and function of …

Capacity of lung stroma to educate dendritic cells inhibiting mycobacteria-specific T-cell response depends upon genetic susceptibility to tuberculosis

MA Kapina, EI Rubakova, KB Majorov, NN Logunova… - PLoS …, 2013 - journals.plos.org
The balance between activation and inhibition of local immune responses in affected tissues
during prolonged chronic infections is important for host protection. There is ample evidence …

The effect of traditional Chinese formula Danchaiheji on the differentiation of regulatory dendritic cells

Y Li, D Chen, X Wang, J Tong, K Li… - Evidence‐Based …, 2016 - Wiley Online Library
Recently, regulatory dendritic cells (DCregs), a newly described dendritic cell subset with
potent immunomodulatory function, have attracted increased attention for their utility in …

Mesenchymal stromal cells in clinical kidney transplantation: how tolerant can it be?

C van Kooten, TJ Rabelink, JW de Fijter… - Current Opinion in …, 2016 - journals.lww.com
This review will discuss the current status of ongoing clinical trials with mesenchymal
stromal cells in kidney transplantation and specifically concentrate on the possibilities and …