By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …

The sensitivity of conventional nuclear magnetic resonance (NMR) techniques is
fundamentally limited by the ordinarily low spin polarization achievable in even the strongest …

Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …

The nuclear spin polarization of the noble gas isotopes 3He and 129Xe can be increased
using optical pumping methods by four to five orders of magnitude. This extraordinary gain …

The study of lung emphysema dates back to the beginning of the 17th century. Nevertheless,
a number of important questions remain unanswered because a quantitative localized …

During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …

Hyperpolarized 3He gas MRI was used to form maps of the effective diffusivity of gas in
human lungs. Images of diffusion as well as spin density are presented from a study of 11 …

PURPOSE: To quantitatively evaluate hyperpolarized helium 3 (3He) diffusion magnetic
resonance (MR) images of the lung in patients with emphysema and to determine whether …

Given its greater availability and lower cost, 129Xe apparent diffusion coefficient (ADC) MRI
offers an alternative to 3He ADC MRI. To demonstrate the feasibility of hyperpolarized …

Lung imaging has traditionally relied on x‐ray methods, since proton MRI is limited to some
extent by low proton density in the lung parenchyma and static field inhomogeneities in the …