[HTML][HTML] Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines
J Bilski, P Pierzchalski, M Szczepanik, J Bonior… - Cells, 2022 - mdpi.com
Obesity and ageing place a tremendous strain on the global healthcare system. Age-related
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …
sarcopenia is characterized by decreased muscular strength, decreased muscle quantity …
Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
A Kalinkovich, G Livshits - Ageing research reviews, 2017 - Elsevier
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
Physiology and role of irisin in glucose homeostasis
N Perakakis, GA Triantafyllou… - Nature reviews …, 2017 - nature.com
Irisin is a myokine that leads to increased energy expenditure by stimulating the'browning'of
white adipose tissue. In the first description of this hormone, increased levels of circulating …
white adipose tissue. In the first description of this hormone, increased levels of circulating …
[HTML][HTML] Physical exercise-induced myokines and muscle-adipose tissue crosstalk: a review of current knowledge and the implications for health and metabolic …
LG Leal, MA Lopes, ML Batista Jr - Frontiers in physiology, 2018 - frontiersin.org
Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic
regimen of regular exercise and pharmaceutical treatment is often recommended for their …
regimen of regular exercise and pharmaceutical treatment is often recommended for their …
[HTML][HTML] Sarcopenic obesity, insulin resistance, and their implications in cardiovascular and metabolic consequences
S Hong, KM Choi - International journal of molecular sciences, 2020 - mdpi.com
The prevalence of sarcopenic obesity is increasing worldwide, particularly amongst aging
populations. Insulin resistance is the core mechanism of sarcopenic obesity and is also …
populations. Insulin resistance is the core mechanism of sarcopenic obesity and is also …
[HTML][HTML] Sarcopenic obesity: an emerging public health problem
T Ji, Y Li, L Ma - Aging and disease, 2022 - ncbi.nlm.nih.gov
Population aging and the obesity epidemic are important global public health problems that
pose an unprecedented threat to the physical and mental health of the elderly and health …
pose an unprecedented threat to the physical and mental health of the elderly and health …
[HTML][HTML] The role of exercise in the interplay between myokines, hepatokines, osteokines, adipokines, and modulation of inflammation for energy substrate …
AM Gonzalez-Gil, L Elizondo-Montemayor - Nutrients, 2020 - mdpi.com
Exercise is an effective strategy for preventing and treating obesity and its related
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …
cardiometabolic disorders, resulting in significant loss of body fat mass, white adipose tissue …
Irisin in metabolic diseases
SA Polyzos, AD Anastasilakis, ZA Efstathiadou… - Endocrine, 2018 - Springer
Introduction Irisin is a myokine/adipokine induced by the exercise in mice and humans,
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …
which is proposed to induce “browning” of white adipose tissue, its primary target, thus …
Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes
TY Liu, CX Shi, R Gao, HJ Sun, XQ Xiong… - Clinical …, 2015 - portlandpress.com
Increased glucose production and reduced hepatic glycogen storage contribute to metabolic
abnormalities in diabetes. Irisin, a newly identified myokine, induces the browning of white …
abnormalities in diabetes. Irisin, a newly identified myokine, induces the browning of white …
[HTML][HTML] Detection and quantitation of circulating human irisin by tandem mass spectrometry
MP Jedrychowski, CD Wrann, JA Paulo, KK Gerber… - Cell metabolism, 2015 - cell.com
Exercise provides many health benefits, including improved metabolism, cardiovascular
health, and cognition. We have shown previously that FNDC5, a type I transmembrane …
health, and cognition. We have shown previously that FNDC5, a type I transmembrane …