From natural sources to synthetic derivatives: The allyl motif as a powerful tool for fragment-based design in cancer treatment
N Astrain-Redin, C Sanmartin… - Journal of Medicinal …, 2023 - ACS Publications
Since the beginning of history, natural products have been an abundant source of bioactive
molecules for the treatment of different diseases, including cancer. Many allyl derivatives …
molecules for the treatment of different diseases, including cancer. Many allyl derivatives …
[HTML][HTML] Assessment of the in-vitro toxicity and in-vivo therapeutic capabilities of Juglans regia on human prostate cancer and prostatic hyperplasia in rats
A Stefanucci, L Marinaccio, EJ Llorent-Martínez… - Food Bioscience, 2024 - Elsevier
Benign prostatic hyperplasia (BPH) and prostatic cancer are aging-associated urological
conditions in men. While significant advances have been made in relation to treatment, poor …
conditions in men. While significant advances have been made in relation to treatment, poor …
Diacerein ameliorates testosterone-induced benign prostatic hyperplasia in rats: Effect on oxidative stress, inflammation and apoptosis
M El-Sherbiny, M El-Shafey, MSE El-Agawy… - International …, 2021 - Elsevier
Benign prostatic hypertrophy (BPH) is a serious medical condition among elderly male
population. BPH pathogenesis has been linked to inflammation, cellular proliferation …
population. BPH pathogenesis has been linked to inflammation, cellular proliferation …
Canagliflozin alleviates experimentally induced benign prostate hyperplasia in a rat model: exploring potential mechanisms involving mir-128b/EGFR/EGF and JAK2 …
Benign prostatic hyperplasia (BPH) poses a significant health concern amongst elderly
males. Canagliflozin (Cana), a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor …
males. Canagliflozin (Cana), a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor …
Chemical and biological studies on Allium sativum L.(1952-2020): A comprehensive review
SST Ahmed, JR Fahim… - Journal of advanced …, 2022 - jabps.journals.ekb.eg
Medicinal plants provide a variety of secondary metabolites with varied chemical structures
and biological activities. Among them, Allium sativum L.(garlic) is one of the most common …
and biological activities. Among them, Allium sativum L.(garlic) is one of the most common …
Combination of lycopene and curcumin synergistically alleviates testosterone-propionate-induced benign prostatic hyperplasia in sprague dawley rats via modulating …
S Wang, W He, W Li, JR Zhou, Z Du - Molecules, 2023 - mdpi.com
Background: Benign prostatic hyperplasia (BPH) is a progressive urological disease
occurring in middle-aged and elderly men, which can be characterized by the non-malignant …
occurring in middle-aged and elderly men, which can be characterized by the non-malignant …
Investigating the therapeutic potential of sinomenine in rheumatoid arthritis: anti-inflammatory, antioxidant, and immunomodulatory mechanisms
J Li, J Cao, Q Chen, D Liu, R Li - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
An autoimmune disease, rheumatoid arthritis (RA) is characterized by the onset of
inflammation and subsequent damage to the joints. Although several therapies are available …
inflammation and subsequent damage to the joints. Although several therapies are available …
Phloretin Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Regulating the Inflammatory Response, Oxidative Stress and Apoptosis
CY Hsu, YS Lin, WC Weng, L Panny, HL Chen… - Life, 2021 - mdpi.com
The inflammatory process is proposed to be one of the factors to benign prostatic
enlargement (BPH), and this is the first study examining the anti-inflammatory ability of …
enlargement (BPH), and this is the first study examining the anti-inflammatory ability of …
Plausible role of oral Fisetin-loaded chitosan oligosaccharide nanoparticles in amelioration of benign prostatic hypertrophy: In vitro and in vivo assessments
Fisetin (FST), a naturally occurring bioactive phytochemical with illustrious pharmacological
activities, has appeared as a potential compound with antioxidant, anti-inflammatory as well …
activities, has appeared as a potential compound with antioxidant, anti-inflammatory as well …
Probenecid ameliorates testosterone‐induced benign prostatic hyperplasia: Implications of PGE‐2 on ADAM‐17/EGFR/ERK1/2 signaling cascade
MM Abdel‐Fattah, ME Abo‐El Fetoh… - … of Biochemical and …, 2023 - Wiley Online Library
Benign prostatic hyperplasia (BPH) is one of the most prevalent clinical disorders in the
elderly. Probenecid (Prob) is a well‐known FDA‐approved therapy for gout owing to its …
elderly. Probenecid (Prob) is a well‐known FDA‐approved therapy for gout owing to its …