Congenital Zika syndrome: genetic avenues for diagnosis and therapy, possible management and long-term outcomes

G Gullo, M Scaglione, G Cucinella, A Riva… - Journal of Clinical …, 2022 - mdpi.com
Zika virus (ZIKV) was discovered in Uganda in 1947 and was originally isolated only in
Africa and Asia. After a spike of microcephaly cases in Brazil, research has closely focused …

Congenital and perinatal infections

B Ostrander, JF Bale - Handbook of clinical neurology, 2019 - Elsevier
Congenital and perinatal infections represent major causes of permanent disability among
children worldwide. Linked together by the acronym TORCH, denoting Toxoplasma gondii …

Clinical and neurodevelopmental features in children with cerebral palsy and probable congenital Zika

A Carvalho, C Brites, G Mochida, P Ventura… - Brain and …, 2019 - Elsevier
Objective To describe the neurological and neurodevelopmental features at 1 year of age in
children with cerebral palsy (CP) related to probable congenital Zika (CZ), followed in a …

Zika virus and the nonmicrocephalic fetus: why we should still worry

CL Walker, MTE Little, JA Roby, B Armistead… - American journal of …, 2019 - Elsevier
Zika virus is a mosquito-transmitted flavivirus and was first linked to congenital microcephaly
caused by a large outbreak in northeastern Brazil. Although the Zika virus epidemic is now …

Association between neonatal neuroimaging and clinical outcomes in Zika-exposed infants from Rio de Janeiro, Brazil

KL Pool, K Adachi, S Karnezis, N Salamon… - JAMA network …, 2019 - jamanetwork.com
Importance Congenital Zika virus (ZIKV) infection may present with a spectrum of clinical
and neuroradiographic findings. Objective To determine whether neuroimaging findings for …

The interplay between brain vascular calcification and microglia

U Maheshwari, SF Huang, S Sridhar… - Frontiers in Aging …, 2022 - frontiersin.org
Vascular calcifications are characterized by the ectopic deposition of calcium and phosphate
in the vascular lumen or wall. They are a common finding in computed tomography scans or …

Neurological complications of congenital Zika virus infection

V de Melo Marques, CS Santos, IG Santiago… - Pediatric …, 2019 - Elsevier
Abstract Background In utero Zika virus infection resulted in many newborns with congenital
defects; this public health issue was followed by unprecedented scientific productivity in this …

Mechanistic insights into bone remodelling dysregulation by human viral pathogens

CCS Caetano, T Azamor, NM Meyer… - Nature …, 2024 - nature.com
Bone-related diseases (osteopathologies) associated with human virus infections have
increased around the globe. Recent findings have highlighted the intricate interplay …

Non-human primate models to investigate mechanisms of infection-associated fetal and pediatric injury, teratogenesis and stillbirth

M Li, A Brokaw, AM Furuta, B Coler… - Frontiers in …, 2021 - frontiersin.org
A wide array of pathogens has the potential to injure the fetus and induce teratogenesis, the
process by which mutations in fetal somatic cells lead to congenital malformations. Rubella …

[HTML][HTML] Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: A living systematic review

MJ Counotte, KW Meili, K Taghavi, G Calvet… - …, 2019 - ncbi.nlm.nih.gov
Background: The Zika virus (ZIKV) caused a large outbreak in the Americas leading to the
declaration of a Public Health Emergency of International Concern in February 2016. A …