Targeting innate immunity in cancer therapy

S Rameshbabu, BW Labadie, A Argulian, A Patnaik - Vaccines, 2021 - mdpi.com
The majority of current cancer immunotherapy strategies target and potentiate antitumor
adaptive immune responses. Unfortunately, the efficacy of these treatments has been limited …

CD36-fatty acid-mediated metastasis via the bidirectional interactions of cancer cells and macrophages

NE Zaidi, NAH Shazali, TC Leow, MA Osman… - Cells, 2022 - mdpi.com
Tumour heterogeneity refers to the complexity of cell subpopulations coexisting within the
tumour microenvironment (TME), such as proliferating tumour cells, tumour stromal cells and …

[HTML][HTML] Crosstalk between fatty acid metabolism and tumour-associated macrophages in cancer progression

NE Zaidi, NAH Shazali, TC Leow, MA Osman… - BioMedicine, 2022 - ncbi.nlm.nih.gov
Over the last few decades, cancer has been regarded as an independent and self sustaining
progression. The earliest hallmarks of cancer comprise of sustaining proliferative signalling …

Dawn era for revisited cancer therapy by innate immune system and immune checkpoint inhibitors

HD Kim, CY Yeh, YC Chang, CH Kim - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
Immunotherapy is a promising therapeutic strategy for cancer. However, it shows limited
efficacy against certain tumor types. The activation of innate immunity can suppress tumors …

Colorectal cancer and immunity: from the wet lab to individuals

E Pramil, C Dillard, AE Escargueil - Cancers, 2021 - mdpi.com
Simple Summary Tackling the current dilemma of colorectal cancer resistance to
immunotherapy is puzzling and requires novel therapeutic strategies to emerge. However …

Exploiting tumor inflammation to increase the therapeutic impact of biguanides in oncology

S Rezzara Richard - 2024 - escholarship.mcgill.ca
Breast cancer is the most common cancer among Canadian women; 1 in 8 women are
expected to develop breast cancer in their lifetime. Breast cancer is grouped into four distinct …

[PDF][PDF] Interleukin-27 Disrupts the Crosstalk of Apoptotic Activities between 4T1 Breast Cancer Cells and M2 Macrophages

NM Yusof, NNMN Fuadi, M Hamid… - Malaysian Journal of …, 2022 - medic.upm.edu.my
Introduction: Cytokine immunotherapy such as Interleukin-27 (IL-27) has been foreseen as a
promising alternative anti-cancer treatment. Thus, this study aimed to investigate whether IL …

[PDF][PDF] Targeting Innate Immunity in Cancer Therapy. Vaccines 2021, 9, 138

S Rameshbabu, BW Labadie, A Argulian, A Patnaik - 2021 - pdfs.semanticscholar.org
The majority of current cancer immunotherapy strategies target and potentiate antitumor
adaptive immune responses. Unfortunately, the efficacy of these treatments has been limited …