Anti-inflammatory and immunomodulatory effects of probiotics in gut inflammation: a door to the body

F Cristofori, VN Dargenio, C Dargenio… - Frontiers in …, 2021 - frontiersin.org
Hosting millions of microorganisms, the digestive tract is the primary and most important part
of bacterial colonization. On one side, in cases of opportunistic invasion, the abundant …

Innate immune dysfunction and neuroinflammation in autism spectrum disorder (ASD)

HK Hughes, RJ Moreno, P Ashwood - Brain, behavior, and immunity, 2023 - Elsevier
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder
characterized by communication and social behavior deficits. The presence of restricted and …

COVID-19 pandemic and impact on patients with autism spectrum disorder

R Baweja, SL Brown, EM Edwards… - Journal of autism and …, 2022 - Springer
The COVID-19 infectious disease pandemic has caused significant fear and uncertainty
around the world and had significant adverse psychological impact. Children, adolescents …

Immune influencers in action: metabolites and enzymes of the tryptophan-kynurenine metabolic pathway

M Tanaka, F Tóth, H Polyák, Á Szabó, Y Mándi… - Biomedicines, 2021 - mdpi.com
The tryptophan (TRP)-kynurenine (KYN) metabolic pathway is a main player of TRP
metabolism through which more than 95% of TRP is catabolized. The pathway is activated …

Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Altered gut microbial profile is associated with abnormal metabolism activity of Autism Spectrum Disorder

Z Dan, X Mao, Q Liu, M Guo, Y Zhuang, Z Liu… - Gut …, 2020 - Taylor & Francis
ABSTRACT Autism Spectrum Disorder (ASD) is a severe neurodevelopmental disorder. To
enhance the understanding of the gut microbiota structure in ASD children at different ages …

The role of maternal immune activation in the pathogenesis of autism: a review of the evidence, proposed mechanisms and implications for treatment

A Zawadzka, M Cieślik, A Adamczyk - International journal of molecular …, 2021 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disease that is characterized by a
deficit in social interactions and communication, as well as repetitive and restrictive …

The Serbian experience of challenges of parenting children with autism spectrum disorders during the COVID-19 pandemic and the state of emergency with lockdown

M Stankovic, A Stojanovic, S Jelena… - European child & …, 2022 - Springer
At the end of 2019, numerous reports of coronavirus infection cases around the world began
to emerge. The disease is characterized by several different symptoms. COVID-19 began to …

Association between epidural analgesia during labor and risk of autism spectrum disorders in offspring

C Qiu, JC Lin, JM Shi, T Chow, VN Desai… - JAMA …, 2020 - jamanetwork.com
Importance Although the safety of labor epidural analgesia (LEA) for neonates has been
well documented, the long-term health effects of LEA on offspring remain to be investigated …

Maternal immune activation induces sustained changes in fetal microglia motility

K Ozaki, D Kato, A Ikegami, A Hashimoto, S Sugio… - Scientific reports, 2020 - nature.com
Maternal infection or inflammation causes abnormalities in brain development associated
with subsequent cognitive impairment and in an increased susceptibility to schizophrenia …