Engineered polymeric iron oxide nanoparticles as potential drug carrier for targeted delivery of docetaxel to breast cancer cells
A biocompatible nanodrug delivery formulation based on poly (D, L-lactide-co-glycolic) acid
(PLGA), polyethylene glycol (PEG) and superparamagnetic iron oxide nanoparticles has …
(PLGA), polyethylene glycol (PEG) and superparamagnetic iron oxide nanoparticles has …
Phosphorothioated amino-AS1411 aptamer functionalized stealth nanoliposome accelerates bio-therapeutic threshold of apigenin in neoplastic rat liver: a …
Hepatocellular carcinoma (HCC) is a leading cause of death globally. Even though the
progressive invention of some very potent therapeutics has been seen, the success is …
progressive invention of some very potent therapeutics has been seen, the success is …
Chitosan-coated nanoparticles enhanced lung pharmacokinetic profile of voriconazole upon pulmonary delivery in mice
Aim: Chitosan-coated polylactic-co-glycolic acid nanoparticles of voriconazole (VChNP)
were developed to increase residence time and provide sustained drug release locally to …
were developed to increase residence time and provide sustained drug release locally to …
Aptamer-functionalized drug nanocarrier improves hepatocellular carcinoma toward normal by targeting neoplastic hepatocytes
S Chakraborty, ZY Dlie, S Chakraborty, S Roy… - … Therapy-Nucleic Acids, 2020 - cell.com
Site-specific delivery of chemotherapeutics specifically to neoplastic hepatocytes without
affecting normal hepatocytes should be a focus for potential therapeutic management of …
affecting normal hepatocytes should be a focus for potential therapeutic management of …
Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo
D Dutta, B Paul, B Mukherjee, L Mondal, S Sen… - Scientific reports, 2019 - nature.com
Betulinic acid, a plant secondary metabolite, has gained significant attention due to its
antiproliferative activity over a range of cancer cells. A promising betulinic acid analogue …
antiproliferative activity over a range of cancer cells. A promising betulinic acid analogue …
Successful delivery of docetaxel to rat brain using experimentally developed nanoliposome: a treatment strategy for brain tumor
Docetaxel (DTX) is found to be very effective against glioma cell in vitro. However, in vivo
passage of DTX through BBB is extremely difficult due to the physicochemical and …
passage of DTX through BBB is extremely difficult due to the physicochemical and …
Aptamer-conjugated apigenin nanoparticles to target colorectal carcinoma: a promising safe alternative of colorectal cancer chemotherapy
Apigenin has gained interest recently among researchers as a potential chemotherapeutic
agent in cancer, including colorectal cancer, due to its established antiproliferative activity in …
agent in cancer, including colorectal cancer, due to its established antiproliferative activity in …
Aptamers for the Delivery of Plant-Based Compounds: A Review
J Gamboa, P Lourenço, C Cruz, E Gallardo - Pharmaceutics, 2024 - mdpi.com
Natural compounds have a high potential for the treatment of various conditions, including
infections, inflammatory diseases, and cancer. However, they usually present poor …
infections, inflammatory diseases, and cancer. However, they usually present poor …
Design, synthesis, anticancer activity, and solid lipid nanoparticle formulation of indole-and benzimidazole-based compounds as pro-apoptotic agents targeting bcl-2 …
Cancer is a multifactorial disease necessitating identification of novel targets for its
treatment. Inhibition of Bcl-2 for triggered pro-apoptotic signaling is considered a promising …
treatment. Inhibition of Bcl-2 for triggered pro-apoptotic signaling is considered a promising …
Development of liposomal formulation for controlled delivery of valacyclovir: an in vitro study
Purpose Herpes, a highly contagious viral infection caused by the herpes simplex virus,
infects the face to any other body part of the skin, even the genital areas. Among the anti …
infects the face to any other body part of the skin, even the genital areas. Among the anti …