Tetrazolium compounds: synthesis and applications in medicine

CX Wei, M Bian, GH Gong - Molecules, 2015 - mdpi.com
Tetrazoles represent a class of five-membered heterocyclic compounds with polynitrogen
electron-rich planar structural features. This special structure makes tetrazole derivatives …

Use of tetrazoles in catalysis and energetic applications: Recent developments

M Nasrollahzadeh, Z Nezafat, NSS Bidgoli, N Shafiei - Molecular Catalysis, 2021 - Elsevier
Increasing interest in tetrazoles and tetrazole based materials in the recent century has been
followed by enormous research efforts devoted for the synthesis of various kinds of materials …

Magnetic chitosan-copper nanocomposite: A plant assembled catalyst for the synthesis of amino-and N-sulfonyl tetrazoles in eco-friendly media

N Motahharifar, M Nasrollahzadeh… - Carbohydrate …, 2020 - Elsevier
A greener, cost efficient and simple method is described to prepare copper nanoparticles
(NPs) immobilized on the magnetic chitosan (one of the more versatile polysaccharides) …

Tetrazoles as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

N Dhiman, K Kaur, V Jaitak - Bioorganic & Medicinal Chemistry, 2020 - Elsevier
Cancer is a leading cause of death worldwide. Even after the availability of numerous drugs
and treatments in the market, scientists and researchers are focusing on new therapies …

Developments in tetrazole chemistry (2009–16)

VA Ostrovskii, EA Popova, RE Trifonov - Advances in heterocyclic chemistry, 2017 - Elsevier
This short review compiles the main results of the studies in tetrazole chemistry published in
the period 2009–2016. Attention is directed to the structure, reactivity, synthetic problems …

Tetrazole hybrids with potential anticancer activity

J Zhang, S Wang, Y Ba, Z Xu - European journal of medicinal chemistry, 2019 - Elsevier
Cancer is one of the main causes of death throughout the world. The anticancer agents are
indispensable for the treatment of various cancers, but most of them currently on the market …

Tetrazole derivatives as promising anticancer agents

EA Popova, AV Protas… - Anti-Cancer Agents in …, 2017 - ingentaconnect.com
Tetrazole cycle is a promising pharmacophore fragment frequently used in the development
of novel drugs. This moiety is a stable, practically non-metabolized bioisosteric analog of …

Platinum and palladium complexes with tetrazole ligands: Synthesis, structure and applications

M Nasrollahzadeh, M Sajjadi, H Ghafuri… - Coordination Chemistry …, 2021 - Elsevier
Research topics/studies on tetrazoles and their complexes have been significantly
increasing in the current century, owing to the exceptional properties of such N-heterocyclic …

Tetrazole: A privileged scaffold for the discovery of anticancer agents

A Verma, B Kaur, S Venugopal… - Chemical Biology & …, 2022 - Wiley Online Library
Carcinoma, characterized by abnormal growth of cells and tissue, is a ubiquitously leading
cause of mortality across the globe due to some carcinogenic factors. Currently, several …

Tetrazoles: A multi-potent motif in drug design

Y Yuan, M Li, V Apostolopoulos, J Matsoukas… - European Journal of …, 2024 - Elsevier
The unique physicochemical properties and fascinating bioisosterism of tetrazole scaffolds
have received significant attention in medicinal chemistry. We report recent efforts using …