[HTML][HTML] Brain-derived estrogen and neural function
Although classically known as an endocrine signal produced by the ovary, 17β-estradiol (E
2) is also a neurosteroid produced in neurons and astrocytes in the brain of many different …
2) is also a neurosteroid produced in neurons and astrocytes in the brain of many different …
Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data
Background The benefits and risks of testosterone treatment for women with diminished
sexual wellbeing remain controversial. We did a systematic review and meta-analysis to …
sexual wellbeing remain controversial. We did a systematic review and meta-analysis to …
Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)
DHEA and DHEAS are steroids synthesized in human adrenals, but their function is unclear.
In addition to adrenal synthesis, evidence also indicates that DHEA and DHEAS are …
In addition to adrenal synthesis, evidence also indicates that DHEA and DHEAS are …
The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents
Rats and mice are attracted by novel objects. They readily approach novel objects and
explore them with their vibrissae, nose and forepaws. It is assumed that such a single …
explore them with their vibrissae, nose and forepaws. It is assumed that such a single …
[HTML][HTML] The International Society for the Study of Women's Sexual Health process of care for management of hypoactive sexual desire disorder in women
AH Clayton, I Goldstein, NN Kim, SE Althof… - Mayo Clinic …, 2018 - Elsevier
Abstract The International Society for the Study of Women's Sexual Health process of care
(POC) for management of hypoactive sexual desire disorder (HSDD) algorithm was …
(POC) for management of hypoactive sexual desire disorder (HSDD) algorithm was …
Neurosteroid biosynthesis: enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides
Neuroactive steroids synthesized in neuronal tissue, referred to as neurosteroids, are
implicated in proliferation, differentiation, activity and survival of nerve cells. Neurosteroids …
implicated in proliferation, differentiation, activity and survival of nerve cells. Neurosteroids …
Forebrain steroid levels fluctuate rapidly during social interactions
L Remage-Healey, NT Maidment, BA Schlinger - Nature neuroscience, 2008 - nature.com
Neurosteroids are powerful modulators of brain function and behavior, yet their dynamics in
the brain have remained elusive. Using in vivo microdialysis in male zebra finches, we found …
the brain have remained elusive. Using in vivo microdialysis in male zebra finches, we found …
Novel mechanisms for neuroendocrine regulation of aggression
KK Soma, MAL Scotti, AEM Newman… - Frontiers in …, 2008 - Elsevier
In 1849, Berthold demonstrated that testicular secretions are necessary for aggressive
behavior in roosters. Since then, research on the neuroendocrinology of aggression has …
behavior in roosters. Since then, research on the neuroendocrinology of aggression has …
Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat …
D Grove-Strawser, MI Boulware, PG Mermelstein - Neuroscience, 2010 - Elsevier
Along with its ability to directly regulate gene expression, estradiol influences cell signaling
and brain functions via rapid, membrane-initiated events. In the female rat striatum, estradiol …
and brain functions via rapid, membrane-initiated events. In the female rat striatum, estradiol …
Estrogen synthesis in the brain—role in synaptic plasticity and memory
Y Hojo, G Murakami, H Mukai, S Higo… - Molecular and cellular …, 2008 - Elsevier
Estrogen and androgen are synthesized from cholesterol locally in hippocampal neurons of
adult animals. These neurosteroids are synthesized by cytochrome P450s and …
adult animals. These neurosteroids are synthesized by cytochrome P450s and …