Multiple myeloma, a quintessential malignant disease of aging: a geroscience perspective on pathogenesis and treatment

VS Urban, A Cegledi, G Mikala - Geroscience, 2023 - Springer
Multiple myeloma (MM) is an incurable plasma cell malignancy, which is predominantly a
disease of older adults (the median age at diagnosis is 70 years). The slow progression from …

Toxicodynamic of combined mycotoxins: MicroRNAs and acute‐phase proteins as diagnostic biomarkers

B Murtaza, X Li, MY Nawaz, MK Saleemi… - … Reviews in Food …, 2024 - Wiley Online Library
Mycotoxins, ubiquitous contaminants in food, present a global threat to human health and
well‐being. Mitigation efforts, such as the implementation of sound agricultural practices …

Osteoclast-derived exosomal miR-5134-5p interferes with Alveolar bone homeostasis by targeting the JAK2/STAT3 Axis

L Pan, C Zhang, H Zhang, T Ke, M Bian… - International Journal …, 2023 - Taylor & Francis
Background In chronic periodontitis, exosomes transport various informative substances
between osteoclasts and osteoblasts in alveolar bone. Herein, we aimed to investigate the …

Comprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival

K Roseth Aass, TMV Nedal… - British Journal of …, 2023 - nature.com
Abstract Background Small RNAs (sRNAs), a heterogenous group of non-coding RNAs, are
emerging as promising molecules for cancer patient risk stratification and as players in …

IL-32 is induced by activation of toll-like receptors in multiple myeloma cells

KR Aass, SS Tryggestad, R Mjelle… - Frontiers in …, 2023 - frontiersin.org
Multiple myeloma (MM) is a hematological cancer characterized by accumulation of
malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer …

Molecular beacon decorated silver nanowires for quantitative miRNA detection by a SERS approach

M Banchelli, S Tombelli, M de Angelis, C D'Andrea… - Analytical …, 2023 - pubs.rsc.org
Advantages of biosensors based on surface enhanced Raman scattering (SERS) rely on
improved sensitivity and specificity, and suited reproducibility in detecting a target molecule …

DMF-DM-seq: Digital-Microfluidics Enabled Dual-Modality Sequencing of Single-Cell mRNA and microRNA with High Integration, Sensitivity, and Automation

Y Chen, X Wang, X Na, Y Zhang, L Cai… - Analytical …, 2024 - ACS Publications
Multimodal measurement of single cells provides deep insights into the intricate
relationships between individual molecular layers and the regulatory mechanisms …

RNA-seq and microRNA association analysis to explore the pathogenic mechanism of DHAV-1 infection with DEHs

W Wang, K Li, T Zhang, H Dong, J Liu - Functional & Integrative Genomics, 2023 - Springer
Duck hepatitis A virus 1 (DHAV-1) is one of the main contagious pathogens that causes
rapid death of ducklings. To illuminate the potential of DHAV-1-infected underlying …

MiR-195-5p is involved in testicular ischemia/reperfusion injury by directly targeting PELP1 and regulating spermatogonia pyroptosis

KX He, L Xu, JZ Ning, F Cheng - International Immunopharmacology, 2023 - Elsevier
Background and objective Ischemia/reperfusion injury (IRI), which is characterized by
testicular torsion and causes permanent impairment of spermatogenic function, is linked with …

[HTML][HTML] MiR-125b targeted regulation of MKNK2 inhibits multiple myeloma proliferation and invasion

B Tan, G Yang, L Su, J Zhou, Y Wu… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Background: An increasing number of studies demonstrate that abnormal miRNA
expression contributes to the advancement of many tumors. Nonetheless, the potential role …