During the past decade metabolomics has emerged as one of the fastest developing
branches of “-omics” technologies. Metabolomics involves documentation, identification, and …

Highlights•Characteristics of the tumor microenvironment that have to be considered for the
development of 3D cell spheroid model systems for translational cancer research.•Methods …

Despite advancements in treatment protocols, cancer is one of the leading cause of deaths
worldwide. Therefore, there is a need to identify newer and personalized therapeutic targets …

We present a quantitative study of the metabolic activity of a single spheroid culture of
human cancer cells. NMR (nuclear magnetic resonance) spectroscopy is an ideal tool for …

Three-dimensional cell cultures are of growing importance in biochemical research as they
represent tissue features more accurately than standard two-dimensional systems, but to …

This is a broad overview and critical review of a particular group of closely related ex vivo
and in vitro metabolic NMR spectroscopic methods. The scope of interest comprises studies …

Omics technologies, such as genomics, epigenomics, transcriptomics, proteomics,
metabolomics, lipidomics, multiomics, and integrated modalities, have greatly contributed to …

Simple Summary Cancer remains one of the leading causes of death worldwide. The
advancements in 3D tumour models provide in vitro test-beds to study cancer growth …

Three‐dimensional (3 D) cell culture platforms are increasingly being used in cancer
research and drug development since they mimic avascular tumors in vitro. In this study, we …

Several lines of evidence indicate that exposure of heart to ionizing radiation increases the
risk of cardiotoxicity manifested by heart dysfunction and cardiovascular diseases. It was …