The design of artificial water channels (AWCs) aims to mimic natural proteins that effectively
mediate the selective transport of water across the bilayer and artificial polymeric …

Self-assembled helical polymers hold great promise as new functional materials, where
helical handedness controls useful properties such as circularly polarized light emission or …

Antimicrobial peptides (AMPs) are expected to be good candidate molecules for novel
antimicrobial therapies. Most AMPs exert their antimicrobial activity through disruption of …

We report here a solid phase synthesis methodology that allows the incorporation of α-
amino acids (X) into quinoline (Q) oligoamide foldamer sequences. Water-soluble hybrid …

Macrocyclic peptides are an important class of bioactive substances. When inserting an
aromatic foldamer segment in a macrocyclic peptide, the strong folding propensity of the …

We present the first examples of atomic-resolution crystal data for the β-peptide 12/10-helix
from oligomers of cis-2-aminocyclohexane carboxylic acid (cis-ACHC) with alternating …

The growth of crystals of aromatic compounds from water much depends on the nature of the
water solubilizing functions that they carry. Rationalizing crystallization from water, and …

Macrocyclization of a stable two‐turn helical aromatic pentamide, that is, an object with
diverging ends that are not prone to cyclization, was made possible by the transient …

A series of quinoline oligoamide foldamers bearing a β-pinene-derived pyridyl group at the
N-terminus or the C-terminus were synthesized, and the efficiencies of chiral inductions …

We report the first atomistic level description of the handedness inversion mechanism for
helical arylamide foldamers. The key process in the handedness inversion is the …