Alzheimer's disease: a review from the pathophysiology to diagnosis, new perspectives for pharmacological treatment

P dos Santos, C Leide, PF Ozela… - Current medicinal …, 2018 - ingentaconnect.com
Dementia is characterized by the impairment of cognition and behavior of people over 65
years. Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the …

[HTML][HTML] Mechanisms of Alzheimer's disease pathogenesis and prevention: the brain, neural pathology, N-methyl-D-aspartate receptors, tau protein and other risk …

S Kocahan, Z Doğan - Clinical Psychopharmacology and …, 2017 - ncbi.nlm.nih.gov
The characteristic features of Alzheimer's disease (AD) are the appearance of extracellular
amyloid-beta (Aβ) plaques and neurofibrillary tangles in the intracellular environment …

Multimodal neuroimaging feature learning with multimodal stacked deep polynomial networks for diagnosis of Alzheimer's disease

J Shi, X Zheng, Y Li, Q Zhang… - IEEE journal of biomedical …, 2017 - ieeexplore.ieee.org
The accurate diagnosis of Alzheimer's disease (AD) and its early stage, ie, mild cognitive
impairment, is essential for timely treatment and possible delay of AD. Fusion of multimodal …

The impact of obesity on neurodegenerative diseases

JN Mazon, AH de Mello, GK Ferreira, GT Rezin - Life sciences, 2017 - Elsevier
Neurodegenerative diseases are a growing health concern. The increasing incidences of
these disorders have a great impact on the patients' quality of life. Although the mechanisms …

[HTML][HTML] Retinal microvascular network attenuation in Alzheimer's disease

MA Williams, AJ McGowan, CR Cardwell… - Alzheimer's & Dementia …, 2015 - Elsevier
Introduction Cerebral small-vessel disease has been implicated in the development of
Alzheimer's disease (AD). The retinal microvasculature enables the noninvasive …

Cognitive impairment and dementia in Parkinson's disease: clinical features, diagnosis, and management

J Meireles, J Massano - Frontiers in neurology, 2012 - frontiersin.org
Parkinson's disease (PD) is a common, disabling, neurodegenerative disorder. In addition to
classical motor symptoms, non-motor features are now widely accepted as part of the clinical …

Circulating microRNAs: a novel class of potential biomarkers for diagnosing and prognosing central nervous system diseases

XF Jin, N Wu, L Wang, J Li - Cellular and molecular neurobiology, 2013 - Springer
As a class of important endogenous small noncoding RNAs that regulate gene expression at
the posttranscriptional level, microRNAs (miRNAs) play a critical role in many physiological …

Mechanistic insight into the role of metformin in Alzheimer's disease

M Sanati, S Aminyavari, AR Afshari, A Sahebkar - Life Sciences, 2022 - Elsevier
Abstract Alzheimer's disease (AD), a type of dementia, is characterized by progressive
memory decline and cognition impairment. Despite the considerable body of evidence …

Downregulated serum miR‐223 servers as biomarker in Alzheimer's disease

LH Jia, YN Liu - Cell biochemistry and function, 2016 - Wiley Online Library
Alzheimer's disease (AD) is an age‐related neurodegenerative disorder that is
characterized by progressive memory loss and deteriorated higher cognitive functions. An …

[图书][B] Thin layer chromatography in drug analysis

L Komsta, M Waksmundzka-Hajnos, J Sherma - 2013 - books.google.com
Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin
layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It …