Cancer stem cells (CSCs) are a subpopulation of cells within tumors that possess the stem
cell characteristics of self-renewal, quiescence, differentiation, and the ability to recapitulate …

Cancer stem cells (CSCs) are subpopulations of tumor cells with the ability to self-renew,
differentiate, and initiate and maintain tumor growth, and they are considered to be the main …

Overwhelming evidence indicates that virtually all treatment-naive tumors contain a
subpopulation of cancer cells that possess some stem cell traits and properties and are …

Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …

IFNγ is conventionally recognized as an inflammatory cytokine that plays a central role in
antitumor immunity. Although it has been used clinically to treat a variety of malignancies …

Background Lung cancer is the most common cause of cancer-related mortality in humans.
There are several reasons for this high rate of mortality, including metastasis to several …

Cancer stem cells (CSCs) have gained an increasing attention recently in cancer research.
CSCs have ability to generate new tumor through their stem cell properties, essentially self …

Emerging evidence has provided important information on oncoproteins involved in cancer
initiation, progression, metastasis, and resistance to current therapies. C-myc, one of the …

The novel information regarding molecular and translational research have created a
paradigm shift in the understanding of lung cancer biology, revealing the more precise target …

Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of
cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism …