Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …

Primary ovarian insufficiency (POI) is determined by exhaustion of follicles in the ovaries,
which leads to infertility before the age of 40 years. It is characterized by a strong familial …

Idiopathic or “unexplained” infertility represents as many as 30% of infertility cases
worldwide. Conception, implantation, and term delivery of developmentally healthy infants …

BACKGROUND Our genetic code is now readable, writable and hackable. The recent
escalation of genome-wide sequencing (GS) applications in population diagnostics will not …

STUDY QUESTION What is the diagnostic potential of next generation sequencing (NGS)
based on a 'mouse azoospermia'gene panel in human non-obstructive azoospermia (NOA) …

Primary ovarian insufficiency (POI) is characterized by amenorrhea, increased follicle-
stimulating hormone (FSH) levels, and hypoestrogenism, leading to infertility before the age …

Premature ovarian insufficiency (POI) is the depletion of ovarian function before 40 years of
age due to insufficient oocyte formation or accelerated follicle atresia. Approximately 1–5 …

Premature ovarian insufficiency (POI) is a major cause of female infertility. It is a
heterogeneous disease that affects about 1% of women under 40 years of age. POI may be …

Primary ovarian insufficiency (POI) affects~ 1–3, 7% of women under forty and is a public
health problem. Most causes are unknown, but an increasing number of genetic causes …

Primary ovarian insufficiency (POI) is a heterogeneous disorder associated with several
genes. The majority of cases are still unsolved. Our aim was to identify the molecular …