Multi-parent populations in crops: a toolbox integrating genomics and genetic mapping with breeding

MF Scott, O Ladejobi, S Amer, AR Bentley, J Biernaskie… - Heredity, 2020 - nature.com
Crop populations derived from experimental crosses enable the genetic dissection of
complex traits and support modern plant breeding. Among these, multi-parent populations …

Genome-wide association studies in maize: praise and stargaze

Y Xiao, H Liu, L Wu, M Warburton, J Yan - Molecular plant, 2017 - cell.com
Genome-wide association study (GWAS) has become a widely accepted strategy for
decoding genotype-phenotype associations in many species thanks to advances in next …

R/qtl2: software for mapping quantitative trait loci with high-dimensional data and multiparent populations

KW Broman, DM Gatti, P Simecek, NA Furlotte… - Genetics, 2019 - academic.oup.com
R/qtl2 is an interactive software environment for mapping quantitative trait loci (QTL) in
experimental populations. The R/qtl2 software expands the scope of the widely-used R/qtl …

Mouse genomic variation and its effect on phenotypes and gene regulation

TM Keane, L Goodstadt, P Danecek, MA White… - Nature, 2011 - nature.com
We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

Y Li, CJ Willer, J Ding, P Scheet… - Genetic …, 2010 - Wiley Online Library
Genome‐wide association studies (GWAS) can identify common alleles that contribute to
complex disease susceptibility. Despite the large number of SNPs assessed in each study …

Applications of single nucleotide polymorphisms in crop genetics

A Rafalski - Current opinion in plant biology, 2002 - Elsevier
The discovery of single nucleotide polymorphisms (SNPs) and insertions/deletions, which
are the basis of most differences between alleles, has been simplified by recent …

MAGIC populations in crops: current status and future prospects

BE Huang, KL Verbyla, AP Verbyla… - Theoretical and Applied …, 2015 - Springer
Key message MAGIC populations present novel challenges and opportunities in crops due
to their complex pedigree structure. They offer great potential both for dissecting genomic …

[HTML][HTML] Genetic mapping of quantitative trait loci in crops

Y Xu, P Li, Z Yang, C Xu - The Crop Journal, 2017 - Elsevier
Dissecting the genetic architecture of complex traits is an ongoing challenge for geneticists.
Two complementary approaches for genetic mapping, linkage mapping and association …

The genetic architecture of quantitative traits

TFC Mackay - Annual review of genetics, 2001 - annualreviews.org
▪ Abstract Phenotypic variation for quantitative traits results from the segregation of alleles at
multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and …

A Multiparent Advanced Generation Inter-Cross to Fine-Map Quantitative Traits in Arabidopsis thaliana

PX Kover, W Valdar, J Trakalo, N Scarcelli… - PLoS …, 2009 - journals.plos.org
Identifying natural allelic variation that underlies quantitative trait variation remains a
fundamental problem in genetics. Most studies have employed either simple synthetic …