Neutrophils and monocytes belong to the first line of immune defence cells and are recruited
to sites of inflammation during infection or sterile injury. Both cells contain huge amounts of …

Neutrophils, eosinophils, and basophils play essential roles during microbe-induced and
sterile inflammation. The severity of such inflammatory processes is controlled, at least in …

S100 protein family has been implicated in multiple stages of tumorigenesis and
progression. Among the S100 genes, 22 are clustered at chromosome locus 1q21, a region …

Pathogen-associated molecular patterns (PAMPs) trigger host immune response by
activating pattern recognition receptors like toll-like receptors (TLRs). However, the …

Recent evidence has revealed an unsuspected suppressive role played by neutrophils
during microbial infections. An especially intriguing aspect of this role is the ability of …

Background Periodontal diseases are inflammatory processes that occur following the influx
of neutrophils into the periodontal tissues in response to the subgingival bacterial biofilm …

Neutrophils and neutrophil extracellular traps (NETs) contribute to the pathogenesis of many
autoimmune diseases, including vasculitis. Though neutrophils, and NETs, can break self …

Background and Objective S100A8 and S100A9, two members of the S100 protein family,
have been reported in association with the tumor cell differentiation and tumor progression …

Autoimmune and auto-inflammatory diseases in children are causing chronic inflammation,
organ damage, and pain. Although several options for treatment are nowadays available a …

Innate myeloid cell (IMC) populations form an essential part of innate immunity. Flow
cytometric (FCM) monitoring of IMCs in peripheral blood (PB) has great clinical potential for …