Exosomes from adipose‐derived stem cells and application to skin wound healing

Y An, S Lin, X Tan, S Zhu, F Nie, Y Zhen, L Gu… - Cell …, 2021 - Wiley Online Library
Skin wound healing is an intractable problem that represents an urgent clinical need. To
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …

Bone physiology as inspiration for tissue regenerative therapies

D Lopes, C Martins-Cruz, MB Oliveira, JF Mano - Biomaterials, 2018 - Elsevier
The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

[HTML][HTML] Extracellular vesicles as signaling mediators and disease biomarkers across biological barriers

P Simeone, G Bologna, P Lanuti… - International journal of …, 2020 - mdpi.com
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …

Microvesicles: ROS scavengers and ROS producers

G Bodega, M Alique, L Puebla… - Journal of …, 2019 - Taylor & Francis
This review analyzes the relationship between microvesicles and reactive oxygen species
(ROS). This relationship is bidirectional; on the one hand, the number and content of …

Circular RNA in exosomes

D Fanale, S Taverna, A Russo, V Bazan - Circular RNAs: biogenesis and …, 2018 - Springer
Circular RNAs (circRNAs) are a novel family of non-coding endogenous RNAs discovered in
all eukaryotic cells and generated through a particular mechanism of alternative splicing …

Bioprocessing of mesenchymal stem cells and their derivatives: Toward cell‐free therapeutics

J Phelps, A Sanati-Nezhad, M Ungrin… - Stem Cells …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) have attracted tremendous research interest due to their
ability to repair tissues and reduce inflammation when implanted into a damaged or …

Platelet‐rich plasma‐derived extracellular vesicles: A superior alternative in regenerative medicine?

J Wu, Y Piao, Q Liu, X Yang - Cell Proliferation, 2021 - Wiley Online Library
Abstract Platelet‐rich plasma (PRP), due to its promising therapeutic properties, has been
used in regenerative medicine for more than 30 years and numerous encouraging outcomes …

Advances in microRNA from adipose-derived mesenchymal stem cell-derived exosome: focusing on wound healing

J Ma, L Yong, P Lei, H Li, Y Fang, L Wang… - Journal of Materials …, 2022 - pubs.rsc.org
Skin wounds are a common condition causing economic burden and they represent an
urgent clinical need, especially chronic wounds. Numerous studies have been conducted on …

[HTML][HTML] Human amniotic fluid stem cell-derived exosomes as a novel cell-free therapy for cutaneous regeneration

Y Zhang, J Yan, Y Liu, Z Chen, X Li, L Tang… - Frontiers in Cell and …, 2021 - frontiersin.org
Adult wound healing often results in fibrotic scarring that is caused by myofibroblast
aggregation. Human amniotic fluid stem cells (hAFSCs) exhibit significantly anti-fibrotic …

[HTML][HTML] Activation of resolution pathways to prevent and fight chronic inflammation: lessons from asthma and inflammatory bowel disease

C Barnig, T Bezema, PC Calder, A Charloux… - Frontiers in …, 2019 - frontiersin.org
Formerly considered as a passive process, the resolution of acute inflammation is now
recognized as an active host response, with a cascade of coordinated cellular and …