Computationally Designed AMPs with Antibacterial and Antibiofilm Activity against MDR Acinetobacter baumannii
The discovery of new antimicrobials is necessary to combat multidrug-resistant (MDR)
bacteria, especially those that infect wounds and form prodigious biofilms, such as …
bacteria, especially those that infect wounds and form prodigious biofilms, such as …
Molecular characterization of extensively drug-resistant hypervirulent Pseudomonas aeruginosa isolates in China
J Li, M Tang, Z Liu, Y Wei, F Xia, Y Xia, Y Hu… - Annals of Clinical …, 2024 - Springer
Background Recently, extensively drug-resistant Pseudomonas aeruginosa (XDR-PA)
isolates have been increasingly detected and posed great challenges to clinical anti …
isolates have been increasingly detected and posed great challenges to clinical anti …
Alternatives to animal models to study bacterial infections
C Hu, W Yang - Folia Microbiologica, 2023 - Springer
Animal testing has made a significant and unequalled contribution to important discoveries
and advancements in the fields of research, medicine, vaccine development, and drug …
and advancements in the fields of research, medicine, vaccine development, and drug …
Characteristics of a Carbapenem-Resistant Acinetobacter baumannii Strain Causing Community-Acquired Pneumonia in a Young Healthy Women
Y Chen, L Xu, J Wang - Infection and Drug Resistance, 2023 - Taylor & Francis
Background Multidrug-resistant Acinetobacter baumannii rarely causes community-acquired
pneumonia. Here, we report the clinical and genomic characteristics of a multidrug-resistant …
pneumonia. Here, we report the clinical and genomic characteristics of a multidrug-resistant …
Zophobas morio larvae as a novel model for the study of Acinetobacter virulence and antimicrobial resistance
N Rakovitsky, E Temkin, A Hameir… - Frontiers in …, 2024 - frontiersin.org
The use of mammalian models for in vivo testing of bacterial virulence raises ethical
concerns and is expensive and time-consuming. As an alternative, non-mammalian models …
concerns and is expensive and time-consuming. As an alternative, non-mammalian models …
Galleria mellonella Invertebrate Model Mirrors the Pathogenic Potential of Mycoplasma alligatoris within the Natural Host
AM Burne, LJ Richey, TR Schoeb… - Transboundary and …, 2024 - Wiley Online Library
Most mycoplasmal infections result in chronic, clinically silent disease. In direct contrast,
Mycoplasma alligatoris elicits a fulminant, multisystem disease in the natural host, Alligator …
Mycoplasma alligatoris elicits a fulminant, multisystem disease in the natural host, Alligator …
Exploring the impact of probiotic route of administration on its protective effects against pathogenic infection in Galleria mellonella
LNK Menta, SKK Law, HS Tan - Journal of the Royal Society of …, 2024 - Taylor & Francis
Identifying promising probiotic candidates for further development remains challenging.
Traditional mammalian models are invaluable for assessing efficacy, but the associated …
Traditional mammalian models are invaluable for assessing efficacy, but the associated …
Transcriptomic Insights into the Virulence of Acinetobacter baumannii During Infection: Role of Iron Uptake and Siderophore Production Genes
Acinetobacter baumannii is a top-priority pathogen as classified by the World Health
Organisation. It causes life-threatening infections in immunocompromised patients, resulting …
Organisation. It causes life-threatening infections in immunocompromised patients, resulting …
Comparison of the virulence of community and hospital isolated Acinetobacter baumannii in HeLa cell line and insect model, Galleria mellonella
Acinetobacter baumannii is an important nosocomial pathogen causing high infections and
morbidity among affected individuals and most studies focus on nosocomial strains …
morbidity among affected individuals and most studies focus on nosocomial strains …