The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

In vitro assays can be useful in determining biological mechanism and optimizing scaffold
parameters, however translation of the in vitro results to clinics is generally hard. Animal …

Background Bone grafts are required to repair large bone defects after tumour resection or
large trauma. The availability of patients' own bone tissue that can be used for these …

The bone immune microenvironment can influence the occurrence and progression of bone
defects. To date, research on promoting macrophage M2 polarization to improve bone injury …

Adipose tissue was only recently considered as a potential source of mesenchymal stem
cells (MSCs) for bone tissue engineering. To improve the osteogenicity of acellular bone …

Introduction: Bone grafting is used to repair large bone defects and autograft is recognised
as producing the best clinical outcome, which is partly due to its cellular component. When …

During the past two decades, with a huge and rapidly increasing clinical need for bone
regeneration and repair, bone substitutes are more and more seen as a potential solution …

Background: Applying 3D printed bioink to bone tissue engineering is an emerging
technology for restoring bone tissue defects. This study aims to evaluate the application of …

The aim of this study was to design a new natural/synthetic bioactive bone scaffold for
potential use in bone replacement applications. We developed a tri-component osteogenic …

We have developed poly (l-lactide-co-glycolide)(PLGA) based composites using sol–gel
derived bioactive glasses (S-BG), previously described by our group, as composite …