Climate change with altered pest-disease dynamics and rising abiotic stresses threatens
resource-constrained agricultural production systems worldwide. Genomics-assisted …

During fertilization, spermatozoa contribute genetic and epigenetic factors that affect early
embryogenesis. Genetic factors include a haploid genome with intact coding regions and …

Major depressive disorder (MDD) is a common complex trait with enormous public health
significance. As part of the Genetic Association Information Network initiative of the US …

Recently, several genome-wide association studies (GWASs) have led to the discovery of
nine new loci of genetic susceptibility in Alzheimer's disease (AD). However, the landscape …

Research on the genetics of natural populations was revolutionized in the 1990s by
methods for genotyping noninvasively collected samples. However, these methods have …

Current evidence suggests that immune system alterations contribute to the etiology of adult
glioma, the most common adult brain tumor. Although previous studies have focused on …

Genome-wide association studies (GWAS) have gained central importance for the
identification of candidate loci underlying complex traits. Single nucleotide polymorphism …

Common genetic variation may play an important role in altering lung cancer risk. We
conducted a pathway-based candidate gene evaluation to identify genetic variations that …

Abstract Background Genome-Wide Association Studies (GWAS) seek to identify causal
genomic variants associated with rare human diseases. The classical statistical approach for …

Genome-wide association studies (GWAS) are increasingly utilized for identifying novel
susceptible genetic variants for complex traits, but there is little consensus on analysis …