The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Stress is an inevitable part of life. Chronic stress on account of reasons like adversity,
depression, anxiety, or loneliness/social isolation can endanger human health. Recent …

Neoadjuvant immune checkpoint blockade (ICB) outperforms adjuvant ICB for treatment of
stage IIIB–D melanoma, but potential biomarkers of response, such as interferon-gamma …

The recently uncovered key role of the peripheral and central nervous systems in controlling
tumorigenesis and metastasis has opened a new area of research to identify innovative …

The peripheral autonomic nervous system (ANS) is known to regulate gene expression in
primary tumours and their surrounding microenvironment. Activation of the sympathetic …

Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …

Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …

Beta-adrenergic signaling has been found to regulate multiple cellular processes that
contribute to the initiation and progression of cancer, including inflammation, angiogenesis …

Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …

Importance Psychological stress contributes to numerous diseases and may do so in part
through damage to telomeres, protective non-coding segments on the ends of …