Clinical aspects of platelet inhibitors and thrombus formation

TA Meadows, DL Bhatt - Circulation research, 2007 - Am Heart Assoc
The platelet, once thought to be solely involved in clot formation, is now known to be a key
mediator in various others processes such as inflammation, thrombosis, and atherosclerosis …

Combination antithrombotic therapies

PA Gurbel, US Tantry - Circulation, 2010 - Am Heart Assoc
or resistant” has been used to describe selected patients, especially high-risk patients and
diabetics, exhibiting high platelet function as measured by assays that are nonspecific in …

Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

KY Chen, SW Rha, YJ Li, KL Poddar, Z Jin, Y Minami… - Circulation, 2009 - Am Heart Assoc
Background—Whether triple antiplatelet therapy is superior or similar to dual antiplatelet
therapy in patients with acute ST-segment elevation myocardial infarction undergoing …

Triple versus dual antiplatelet therapy after coronary stenting: impact on stent thrombosis

SW Lee, SW Park, MK Hong, YH Kim, BK Lee… - Journal of the American …, 2005 - jacc.org
Objectives: We evaluated safety and efficacy of triple antiplatelet therapy with aspirin,
clopidogrel, or ticlopidine and cilostazol after coronary stenting. Background: Triple …

A randomized study assessing the impact of cilostazol on platelet function profiles in patients with diabetes mellitus and coronary artery disease on dual antiplatelet …

DJ Angiolillo, P Capranzano, S Goto… - European heart …, 2008 - academic.oup.com
Aims Patients with type 2 diabetes mellitus (T2DM) have reduced platelet inhibition
compared with non-diabetics following P2Y12 receptor blockade. Whether inhibition of …

Randomized comparison of adjunctive cilostazol versus high maintenance dose clopidogrel in patients with high post-treatment platelet reactivity: results of the …

YH Jeong, SW Lee, BR Choi, IS Kim, MK Seo… - Journal of the American …, 2009 - jacc.org
Objectives: The purpose of this study was to determine the impact of adjunctive cilostazol in
patients with high post-treatment platelet reactivity (HPPR) undergoing coronary stenting …

Cilostazol in addition to aspirin and clopidogrel improves long-term outcomes after percutaneous coronary intervention in patients with acute coronary syndromes: a …

Y Han, Y Li, S Wang, Q Jing, Z Wang, D Wang… - American heart …, 2009 - Elsevier
BACKGROUND: Cilostazol has been widely used to prevent peripheral vascular events, and
its antiplatelet mechanisms may different from aspirin and clopidogrel. We hypothesized that …

Clopidogrel: a review of its use in the prevention of thrombosis

GL Plosker, KA Lyseng-Williamson - Drugs, 2007 - Springer
Summary Abstract Clopidogrel (Plavix®, Iscover®) selectively and irreversibly inhibits
adenosine diphosphate (ADP)-induced platelet aggregation. Long-term administration of …

Systematic review and meta-analysis of randomized clinical trials appraising the impact of cilostazol after percutaneous coronary intervention

GGL Biondi-Zoccai, M Lotrionte, M Anselmino… - American heart …, 2008 - Elsevier
BACKGROUND: Drug-eluting stents reduce the risk of restenosis after percutaneous
coronary intervention (PCI) but may pose a risk of thrombosis. Cilostazol, an oral antiplatelet …

Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE–Long Trial)

SW Lee, SW Park, YH Kim, SC Yun, DW Park… - The American journal of …, 2007 - Elsevier
To evaluate the impact of cilostazol on neointimal hyperplasia after drug-eluting stent (DES)
implantation for long coronary lesions, we performed a randomized multicenter prospective …