Circulating microRNAs in cancer: origin, function and application
R Ma, T Jiang, X Kang - Journal of experimental & clinical cancer research, 2012 - Springer
MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression
at the posttranscriptional level. The dysregulation of miRNAs has been linked to a series of …
at the posttranscriptional level. The dysregulation of miRNAs has been linked to a series of …
Circulating miRNAs in cancer: from detection to therapy
WT Wang, YQ Chen - Journal of hematology & oncology, 2014 - Springer
Since the discovery of circulating microRNAs (miRNAs) in body fluids, an increasing number
of studies have focused on their potential as non-invasive biomarkers and as therapeutic …
of studies have focused on their potential as non-invasive biomarkers and as therapeutic …
Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome
Psoriasis is a chronic and complex inflammatory skin disease with lesions displaying
dramatically altered mRNA expression profiles. However, much less is known about the …
dramatically altered mRNA expression profiles. However, much less is known about the …
miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs
M Riaz, MTM van Jaarsveld, A Hollestelle… - Breast cancer …, 2013 - Springer
Introduction Breast cancer is a genetically and phenotypically complex disease. To
understand the role of miRNAs in this molecular complexity, we performed miRNA …
understand the role of miRNAs in this molecular complexity, we performed miRNA …
Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration
The progression of cancer to metastatic disease is a major cause of death. We identified miR-
708 being transcriptionally repressed by polycomb repressor complex 2-induced H3K27 …
708 being transcriptionally repressed by polycomb repressor complex 2-induced H3K27 …
Different miRNA expression profiles between human breast cancer tumors and serum
J Zhu, Z Zheng, J Wang, J Sun, P Wang, X Cheng… - Frontiers in …, 2014 - frontiersin.org
A bunch of microRNAs (miRNAs) have been demonstrated to be aberrantly expressed in
cancer tumor tissue and serum. The miRNA signatures identified from the serum samples …
cancer tumor tissue and serum. The miRNA signatures identified from the serum samples …
A deep sequencing approach to uncover the miRNOME in the human heart
S Leptidis, H El Azzouzi, SI Lok, R de Weger… - PloS one, 2013 - journals.plos.org
MicroRNAs (miRNAs) are a class of non-coding RNAs of∼ 22 nucleotides in length, and
constitute a novel class of gene regulators by imperfect base-pairing to the 3′ UTR of …
constitute a novel class of gene regulators by imperfect base-pairing to the 3′ UTR of …
Circulating microRNAs: potential biomarkers for common malignancies
S Khoury, N Tran - Biomarkers in medicine, 2015 - Taylor & Francis
MicroRNAs (miRNAs) belong to a class of small noncoding RNAs (ncRNAs), which regulate
gene expression at the post-transcriptional level. They are approximately 22 nucleotide …
gene expression at the post-transcriptional level. They are approximately 22 nucleotide …
Extracellular RNAs: development as biomarkers of human disease
Ten ongoing studies designed to test the possibility that extracellular RNAs may serve as
biomarkers in human disease are described. These studies, funded by the NIH Common …
biomarkers in human disease are described. These studies, funded by the NIH Common …
Profiling cell-free and circulating miRNA: a clinical diagnostic tool for different cancers
C Chakraborty, S Das - Tumor Biology, 2016 - Springer
Effective cancer management depends on early diagnosis and treatment. There are several
microRNAs (miRNAs) which are used for detection of various cancers. Cell-free and …
microRNAs (miRNAs) which are used for detection of various cancers. Cell-free and …