[HTML][HTML] Colorectal cancer diagnosis: the obstacles we face in determining a non-invasive test and current advances in biomarker detection

F Kamel, K Eltarhoni, P Nisar, M Soloviev - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is one of the most common cancers in the
western world. CRC originates from precursor adenomatous polyps, which may over time …

Molecular biomarkers for an early diagnosis, effective treatment and prognosis of colorectal cancer: Current updates

A Mahasneh, F Al-Shaheri, E Jamal - Experimental and molecular …, 2017 - Elsevier
Colorectal cancer (CRC) is the third most prevalent cancer in the world. Globally, it has been
estimated that about 1.4 million new cases of colorectal cancer are diagnosed every year …

Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus

HR Moinova, T LaFramboise, JD Lutterbaugh… - Science translational …, 2018 - science.org
We report a biomarker-based non-endoscopic method for detecting Barrett's esophagus
(BE) based on detecting methylated DNAs retrieved via a swallowable balloon-based …

Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1

Y Guo, L Shu, C Zhang, ZY Su, ANT Kong - Biochemical pharmacology, 2015 - Elsevier
Colorectal cancer remains the most prevalent malignancy in humans. The impact of
epigenetic alterations on the development of this complex disease is now being recognized …

Genome-wide germline correlates of the epigenetic landscape of prostate cancer

KE Houlahan, YJ Shiah, A Gusev, J Yuan, M Ahmed… - Nature medicine, 2019 - nature.com
Oncogenesis is driven by germline, environmental and stochastic factors. It is unknown how
these interact to produce the molecular phenotypes of tumors. We therefore quantified the …

[HTML][HTML] Aberrantly hypermethylated tumor suppressor genes were identified in oral squamous cell carcinoma (OSCC)

SY Kim, YK Han, JM Song, CH Lee, K Kang, JM Yi… - Clinical …, 2019 - Springer
Background Oral squamous cell carcinoma (OSCC) is a genetic and epigenetic disease.
There is growing evidence to suggest that environmental factors due to epigenetic changes …

Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer

SA Farkas, N Milutin-Gašperov, M Grce, TK Nilsson - Epigenetics, 2013 - Taylor & Francis
The oncogenic human papilloma viruses (HPVs) are associated with precancerous cervical
lesions and development of cervical cancer. The DNA methylation signatures of the host …

Evaluation of FTIR spectroscopy as diagnostic tool for colorectal cancer using spectral analysis

L Dong, X Sun, Z Chao, S Zhang, J Zheng… - … Acta Part A: Molecular …, 2014 - Elsevier
The aim of this study is to confirm FTIR spectroscopy as a diagnostic tool for colorectal
cancer. 180 freshly removed colorectal samples were collected from 90 patients for …

DNA methylation dynamics in plants and mammals: overview of regulation and dysregulation

AR Elhamamsy - Cell biochemistry and function, 2016 - Wiley Online Library
DNA methylation is a major epigenetic marking mechanism regulating various biological
functions in mammals and plant. The crucial role of DNA methylation has been observed in …

[HTML][HTML] Cancer-associated stromal fibroblast-derived transcriptomes predict poor clinical outcomes and immunosuppression in colon cancer

J Wang, R Akter, MF Shahriar… - Pathology and Oncology …, 2022 - por-journal.com
Background: Previous studies revealed that colonic cancer-associated fibroblasts (CAFs)
are associated with the modulation of the colon tumor microenvironment (TME). However …