Various parental characteristics, including psychiatric disorders and parenting behaviours,
are associated with offspring mental health and related outcomes in observational studies …

Background Genetic influences are ubiquitous as virtually all phenotypes and most
exposures typically classified as environmental have been found to be heritable. A …

Distinguishing between the effects of nature and nurture constitutes a major research goal
for those interested in understanding human development. It is known, for example, that …

In this review, we discuss how samples comprising monozygotic and dizygotic twin pairs can
be used for the purpose of strengthening causal inference by controlling for shared …

Objective To investigate the genetic architecture of internalizing symptoms in childhood and
adolescence. Method In 22 cohorts, multiple univariate genome-wide association studies …

Background Fundamental questions about the roles of genes, environments, and their
interplay in developmental psychopathology have traditionally been the domain of twin and …

Objective Parent anxiety is associated with offspring internalizing problems (emotional
problems related to anxiety and depression). This may reflect causal processes, whereby …

Linking the developing brain with individual differences in clinical and demographic traits is
challenging due to the substantial interindividual heterogeneity of brain anatomy and …

Background Although polygenic risk scores (PRS) predict psychiatric problems, these
associations might be attributable to indirect pathways including population stratification …

Maternal depressive symptoms are highly prevalent and can negatively impact affected
individuals and family members. Understanding etiological influences on maternal …