Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

Toward higher-performance bionic limbs for wider clinical use

D Farina, I Vujaklija, R Brånemark, AMJ Bull… - Nature biomedical …, 2023 - nature.com
Most prosthetic limbs can autonomously move with dexterity, yet they are not perceived by
the user as belonging to their own body. Robotic limbs can convey information about the …

Restoration of sensory information via bionic hands

SJ Bensmaia, DJ Tyler, S Micera - Nature Biomedical Engineering, 2023 - nature.com
Individuals who have lost the use of their hands because of amputation or spinal cord injury
can use prosthetic hands to restore their independence. A dexterous prosthesis requires the …

From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks

S Lee, Q Shi, C Lee - APL Materials, 2019 - pubs.aip.org
Flexible electronics technology dramatically changes the capability of sensors, which allows
us to detect human biological signals not only on the skin but also inside the human body …

A review for the peripheral nerve interface designer

CE Larson, E Meng - Journal of neuroscience methods, 2020 - Elsevier
Informational density and relative accessibility of the peripheral nervous system make it an
attractive site for therapeutic intervention. Electrode-based electrophysiological interfaces …

Compliant peripheral nerve interfaces

V Paggi, O Akouissi, S Micera… - Journal of neural …, 2021 - iopscience.iop.org
Peripheral nerve interfaces (PNIs) record and/or modulate neural activity of nerves, which
are responsible for conducting sensory-motor information to and from the central nervous …

Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

M Cracchiolo, MM Ottaviani, A Panarese… - Journal of Neural …, 2021 - iopscience.iop.org
Bioelectronic medicine (BM) is an emerging new approach for developing novel
neuromodulation therapies for pathologies that have been previously treated with …

Interfaces with the peripheral nervous system for the control of a neuroprosthetic limb: a review

KA Yildiz, AY Shin, KR Kaufman - Journal of neuroengineering and …, 2020 - Springer
The field of prosthetics has been evolving and advancing over the past decade, as patients
with missing extremities are expecting to control their prostheses in as normal a way as …

Biomedical and tissue engineering strategies to control foreign body reaction to invasive neural electrodes

M Gori, G Vadalà, SM Giannitelli, V Denaro… - … in Bioengineering and …, 2021 - frontiersin.org
Neural-interfaced prostheses aim to restore sensorimotor limb functions in amputees. They
rely on bidirectional neural interfaces, which represent the communication bridge between …

A guide towards long-term functional electrodes interfacing neuronal tissue

AF Renz, AM Reichmuth, F Stauffer… - Journal of Neural …, 2018 - iopscience.iop.org
Implantable electronics address therapeutical needs of patients with electrical signaling
dysfunctions such as heart problems, neurological disorders or hearing impairments. While …