Bladder cancer is among the ten most common cancers globally, causes considerable
morbidity and mortality and is, therefore, a substantial burden for health-care systems. The …

Retinoblastoma management remains complex, requiring individualized treatment based on
International Classification of Retinoblastoma (ICRB) staging, germline mutation status …

Pediatric osteosarcoma is characterized by multiple somatic chromosomal lesions, including
structural variations (SVs) and copy number alterations (CNAs). To define the landscape of …

Retinoblastoma is an aggressive eye cancer of infancy and childhood. Survival and the
chance of saving vision depend on severity of disease at presentation. Retinoblastoma was …

Retinoblastoma (Rb) is the most common primary intraocular malignancy of childhood, but
an uncommon paediatric cancer, with a constant incidence worldwide of 1: 15,000–1 …

The retinoblastoma (RB) tumour suppressor gene is functionally inactivated in a broad
range of paediatric and adult cancers, and a plethora of cellular functions and partners have …

Retinoblastoma (RB) is the most common intraocular malignancy in childhood.
Approximately 40% of retinoblastomas are hereditary and due to germline mutations in the …

Retinoblastoma is lethal by metastasis if left untreated, so the primary goal of therapy is to
preserve life, with ocular survival, visual preservation and quality of life as secondary aims …

Sarcomas make up a broad group of malignant neoplasms of mesenchymal origin. More
than 70 histologic subtypes have been identified. However, sarcomas can be classified into …

Improvements in early detection, supportive care, and treatment have resulted in an
increasing number of cancer survivors, with a current 5-year relative survival rate for all …