Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

The cysteine (Cys) proteome is a major component of the adaptive interface between the
genome and the exposome. The thiol moiety of Cys undergoes a range of biologic …

During ethanol fermentation, yeast cells encounter various stresses including sugar
substrates-induced high osmolarity, increased ethanol concentration, oxygen metabolism …

Significance: Glutathione metabolism is comparable to a jigsaw puzzle with too many
pieces. It is supposed to comprise (i) the reduction of disulfides, hydroperoxides, sulfenic …

Significance: Glutathione (GSH) is the most abundant cellular low-molecular-weight thiol in
the majority of organisms in all kingdoms of life. Therefore, functions of GSH and disturbed …

The volatile organic sulfur compound allicin (diallyl thiosulfinate) is produced as a defense
substance when garlic (Allium sativum) tissues are damaged, for example by the activities of …

Synthetic biology tools, such as modular parts and combinatorial DNA assembly, are
routinely used to optimise the productivity of heterologous metabolic pathways for …

Ageing cells undergo changes in redox homeostasis and acquire high levels of reactive
oxygen species (ROS). Because accumulation of ROS involves a change in redox state of …

Many metabolic diseases disrupt endoplasmic reticulum (ER) homeostasis, but little is
known about how metabolic activity is communicated to the ER. Here, we show in …

Autophagy is a membrane-trafficking process whereby double-membrane vesicles called
autophagosomes engulf and deliver intracellular material to the vacuole for degradation …