Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer's
disease (AD) and, as such, have become the focus of therapeutic development. Recent …

Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

Evidence of reduced blood-brain barrier (BBB) integrity preceding other Alzheimer's disease
(AD) pathology provides a strong link between cerebrovascular angiopathy and AD …

Age is a common risk factor for Alzheimer's disease (AD) and age-related macular
degeneration (AMD). Because of the increasing age of the population, these two age-related …

Alzheimer's disease (AD) progressively inflicts impairment of synaptic functions with notable
deposition of amyloid-β (Aβ) as senile plaques within the extracellular space of the brain …

The chick embryo chorioallantoic membrane (CAM) is an extraembryonic membrane
mediating gas and nutrient exchanges until hatching. Since it has a dense capillary network …

Amyloidogenicity and vascular dysfunction are the key players in the pathogenesis of
Alzheimer's disease (AD), involving dysregulated cellular interactions. An intricate balance …

Alterations in the blood brain barrier and brain vasculature may be involved in
neurodegeneration and neuroinflammation. We sought to determine if vascular remodeling …

Alzheimer's disease (AD) is a progressive chronic disorder and is characterized by β-
amyloid plaques and angiopathy, tau pathology, neuronal cell death, and inflammatory …

Cerebrovascular dysfunction is rapidly reemerging as a major process of Alzheimer's
disease (AD). It is, therefore, crucial to delineate the roles of AD risk factors in …