Microglial cell activation is a rapidly occurring cellular response to cerebral ischaemia.
Microglia proliferate, are recruited to the site of lesion, npregulate the expression of several …

Levels of glial fibrillary acidic protein (GFAP), an astrocyte‐specific intermediate filament
protein, are altered during development and aging, GFAP also responds dynamically to …

The epigenetic signals that regulate lineage development in the embryonic mammalian
brain are poorly understood. Here we demonstrate that a specific subclass of the …

Glial fibrillary acidic protein (GFAP) mRNA was examined by RNA blot hybridization in three
age groups of two cohorts of male F-344 rats and in 47 human postmortem brain samples …

In the central nervous system (CNS), nerve regeneration after traumatic injury fails. The
formation of a dense fibrous scar is thought to restrict in part the growth of axonal …

Entorhinal cortex lesions (ECL) that damage the perforant path to the hippocampus induce
rapid increases of apolipoprotein E (apo E) mRNA in the hippocampus. Apo E mRNA was …

It is becoming clear that transforming growth factor β (TGFβ) may be a key factor regulating
inflammatory and tissue specific wound responses. Because the formation of a glial …

Factors involved in the control of the biological properties of gliomas, the major form of brain
tumour in man, are poorly documented. We investigated the role of transforming growth …

Transection of the rat facial nerve leads to a rapid activation of both astrocytes and microglia
around axotomized motoneurons. The factors involved in glial activation in vivo are poorly …

Lesions to the nervous system are nearly universally accompanied by a glial response
involving both microglia and astrocytes. The growth and immunoregulatory cytokine …