Structure determination of membrane proteins by NMR spectroscopy

SJ Opella, FM Marassi - Chemical reviews, 2004 - ACS Publications
Much of postgenomic biochemistry and all of structural biology are based on the premise
that the starting point for both understanding specific biochemical processes, such as affinity …

Weak alignment NMR: a hawk-eyed view of biomolecular structure

A Bax, A Grishaev - Current opinion in structural biology, 2005 - Elsevier
Imposing a very slight deviation from the isotropic random distribution of macromolecules in
solution in an NMR sample tube permits the measurement of residual internuclear dipolar …

Structure of the chemokine receptor CXCR1 in phospholipid bilayers

SH Park, BB Das, F Casagrande, Y Tian, HJ Nothnagel… - Nature, 2012 - nature.com
CXCR1 is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8), a
major mediator of immune and inflammatory responses implicated in many disorders …

Three-dimensional structure of the channel-forming trans-membrane domain of virus protein “u”(Vpu) from HIV-1

SH Park, AA Mrse, AA Nevzorov, MF Mesleh… - Journal of molecular …, 2003 - Elsevier
The three-dimensional structure of the channel-forming trans-membrane domain of virus
protein “u”(Vpu) of HIV-1 was determined by NMR spectroscopy in micelle and bilayer …

[图书][B] Structure in protein chemistry

J Kyte - 2006 - books.google.com
The second edition of Structure in Protein Chemistry showcases the latest developments
and innovations in the field of protein structure analysis and prediction. The book begins by …

Concepts and methods of solid-state NMR spectroscopy applied to biomembranes

TR Molugu, S Lee, MF Brown - Chemical reviews, 2017 - ACS Publications
Concepts of solid-state NMR spectroscopy and applications to fluid membranes are
reviewed in this paper. Membrane lipids with 2H-labeled acyl chains or polar head groups …

When detergent meets bilayer: birth and coming of age of lipid bicelles

UHN Dürr, R Soong, A Ramamoorthy - Progress in nuclear magnetic …, 2013 - Elsevier
► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

[HTML][HTML] Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR

E Strandberg, S Özdirekcan, DTS Rijkers… - Biophysical journal, 2004 - cell.com
Solid-state NMR methods employing 2 H NMR and geometric analysis of labeled alanines
(GALA) were used to study the structure and orientation of the transmembrane α-helical …

NMR methods for studying membrane‐active antimicrobial peptides

E Strandberg, AS Ulrich - … in Magnetic Resonance Part A: An …, 2004 - Wiley Online Library
NMR is a versatile tool for studying interactions between antimicrobial peptides and lipid
membranes. Different approaches using both liquid state and solid state NMR are outlined …

NMR study of the tetrameric KcsA potassium channel in detergent micelles

JH Chill, JM Louis, C Miller, A Bax - Protein Science, 2006 - Wiley Online Library
Nuclear magnetic resonance (NMR) studies of large membrane‐associated proteins are
limited by the difficulties in preparation of stable protein–detergent mixed micelles and by …