The vascular endothelium is an interface between the blood stream and the vessel wall.
Changes in this single cell layer of the artery wall are believed of primary importance in the …

Statins, among the most commonly prescribed drugs worldwide, are cholesterol-lowering
agents used to manage and prevent cardiovascular and coronary heart diseases. Recently …

▪ Abstract Statins are potent inhibitors of cholesterol biosynthesis. In clinical trials, statins are
beneficial in the primary and secondary prevention of coronary heart disease. However, the …

Background Endothelial progenitor cells derived from bone marrow are believed to support
the integrity of the vascular endothelium. The number and function of endothelial progenitor …

Postnatal bone marrow contains a subtype of progenitor cells that have the capacity to
migrate to the peripheral circulation and to differentiate into mature endothelial cells …

Common conditions predisposing to atherosclerosis, such as hypercholesterolemia,
hypertension, diabetes, and smoking, are associated with endothelial dysfunction …

Background—The molecular mechanisms by which physical training improves peripheral
and coronary artery disease are poorly understood. Bone marrow–derived endothelial …

Endothelial cell damage is one important pathophysiological step of atherosclerosis and
restenosis after angioplasty. Accelerated reendothelialization impairs neointima formation …

The accumulation of smooth muscle and endothelial cells is essential for remodeling and
repair of injured blood vessel walls. Bone marrow–derived progenitor cells have been …

Bone marrow and peripheral blood of adults contain a special sub‐type of progenitor cells
which are able to differentiate into mature endothelial cells, thus contributing to re …