Although more studies are demonstrating that a father's environment can influence child
health and disease, the molecular mechanisms underlying non-genetic inheritance remain …

BACKGROUND Studies in non-human mammals suggest that environmental factors can
influence spermatozoal DNA methylation, and some research suggests that spermatozoal …

Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

Background Children of aged fathers are at a higher risk of developing mental disorders.
Alterations in sperm DNA methylation have been implicated as a potential cause. However …

The paternal environment has been linked to infertility and negative outcomes. Such effects
may be transmitted via sperm through histone modifications. To date, in-depth profiling of the …

Assisted reproductive technologies (ART) account for 1–6% of births in developed countries.
While most children conceived are healthy, increases in birth and genomic imprinting …

Background: The organochlorine dichlorodiphenyltrichloroethane (DDT) is banned
worldwide owing to its negative health effects. It is exceptionally used as an insecticide for …

Background Women of reproductive age are recommended to consume folic acid and other
supplements before conception and during pregnancy. We aimed to investigate the …

Background Children conceived through assisted reproduction are at an increased risk for
growth and genomic imprinting disorders, often linked to DNA methylation defects. It has …

Background DNA methylation (DNAme) erasure and reacquisition occur during prenatal
male germ cell development; some further remodeling takes place after birth during …