RNA interference for mosquito and mosquito-borne disease control
PM Airs, LC Bartholomay - Insects, 2017 - mdpi.com
RNA interference (RNAi) is a powerful tool to silence endogenous mosquito and mosquito-
borne pathogen genes in vivo. As the number of studies utilizing RNAi in basic research …
borne pathogen genes in vivo. As the number of studies utilizing RNAi in basic research …
Improving suppression of hemipteran vectors and bacterial pathogens of citrus and solanaceous plants: advances in antisense oligonucleotides (FANA)
We report on the development, evaluation, and efficient delivery of antisense
oligonucleotide FANA (2′-deoxy-2′-fluoro-arabinonucleotide) RNA-targeting technology …
oligonucleotide FANA (2′-deoxy-2′-fluoro-arabinonucleotide) RNA-targeting technology …
Optimizing efficient RNAi-mediated control of hemipteran pests (psyllids, leafhoppers, whitefly): modified pyrimidines in dsRNA triggers
WB Hunter, WM Wintermantel - Plants, 2021 - mdpi.com
The advantages from exogenously applied RNAi biopesticides have yet to be realized in
through commercialization due to inconsistent activity of the dsRNA trigger, and the activity …
through commercialization due to inconsistent activity of the dsRNA trigger, and the activity …
Inhibition of JNK signaling in the Asian malaria vector Anopheles stephensi extends mosquito longevity and improves resistance to Plasmodium falciparum infection
L Souvannaseng, LV Hun, H Baker, JM Klyver… - PLoS …, 2018 - journals.plos.org
Malaria is a global health concern caused by infection with Plasmodium parasites. With
rising insecticide and drug resistance, there is a critical need to develop novel control …
rising insecticide and drug resistance, there is a critical need to develop novel control …
Plasmodium falciparum suppresses the host immune response by inducing the synthesis of insulin-like peptides (ILPs) in the mosquito Anopheles stephensi
The insulin-like peptides (ILPs) and their respective signaling and regulatory pathways are
highly conserved across phyla. In invertebrates, ILPs regulate diverse physiological …
highly conserved across phyla. In invertebrates, ILPs regulate diverse physiological …
Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential
Malaria parasites alter mosquito feeding behaviour in a way that enhances parasite
transmission. This is widely considered a prime example of manipulation of host behaviour …
transmission. This is widely considered a prime example of manipulation of host behaviour …
Genetic technologies for disease vectors
F Criscione, DA O'Brochta, W Reid - Current opinion in insect science, 2015 - Elsevier
Highlights•The first genetic technologies for insect vectors of disease were introduced 20
years ago.•Today there are 12 classes of genetic technologies being used in insect vectors …
years ago.•Today there are 12 classes of genetic technologies being used in insect vectors …
Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi
Background Insecticides are still at the core of insect pest and vector control programmes.
Several lines of evidence indicate that ABC transporters are involved in detoxification …
Several lines of evidence indicate that ABC transporters are involved in detoxification …
Protein kinase inhibitors as potential antimicrobial drugs against tuberculosis, malaria and HIV
Infectious diseases that are caused by pathogenic microbes such as bacteria, viruses,
parasites or fungi remain the top major cause of death across the world, particularly in low …
parasites or fungi remain the top major cause of death across the world, particularly in low …
Evidence for Divergent Selection on Immune Genes between the African Malaria Vectors, Anopheles coluzzii and A. gambiae
Simple Summary A comparison of the genomes of the African malaria vectors, Anopheles
gambiae and A. coluzzii, revealed that immune genes are highly diverged. Although these …
gambiae and A. coluzzii, revealed that immune genes are highly diverged. Although these …