Emerging coronaviruses: genome structure, replication, and pathogenesis

Y Chen, Q Liu, D Guo - Journal of medical virology, 2020 - Wiley Online Library
The recent emergence of a novel coronavirus (2019‐nCoV), which is causing an outbreak of
unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of …

The proteins of severe acute respiratory syndrome coronavirus-2 (SARS CoV-2 or n-COV19), the cause of COVID-19

FK Yoshimoto - The protein journal, 2020 - Springer
The devastating effects of the recent global pandemic (termed COVID-19 for “coronavirus
disease 2019”) caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV …

The molecular virology of coronaviruses

E Hartenian, D Nandakumar, A Lari, M Ly… - Journal of Biological …, 2020 - ASBMB
Few human pathogens have been the focus of as much concentrated worldwide attention as
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19. Its …

[HTML][HTML] Natural history of COVID-19 and current knowledge on treatment therapeutic options

WG Dos Santos - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Despite intense research there is currently no effective vaccine available against the new
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in the later 2019 …

COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties

M Asif, M Saleem, M Saadullah, HS Yaseen… - …, 2020 - Springer
Abstract Coronavirus disease of 2019 (COVID-19) has emerged as a global health threat.
Unfortunately, there are very limited approved drugs available with established efficacy …

Crystal structure of Nsp15 endoribonuclease NendoU from SARS‐CoV‐2

Y Kim, R Jedrzejczak, NI Maltseva… - Protein …, 2020 - Wiley Online Library
Abstract Severe Acute Respiratory Syndrome coronavirus 2 (SARS‐CoV‐2) is rapidly
spreading around the world. There is no existing vaccine or proven drug to prevent …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

Essential oils as antiviral agents, potential of essential oils to treat SARS-CoV-2 infection: an in-silico investigation

JKR Da Silva, PLB Figueiredo, KG Byler… - International journal of …, 2020 - mdpi.com
Essential oils have shown promise as antiviral agents against several pathogenic viruses. In
this work we hypothesized that essential oil components may interact with key protein …

Coronaviruses: an overview of their replication and pathogenesis

AR Fehr, S Perlman - Coronaviruses: methods and protocols, 2015 - Springer
Abstract Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized
by club-like spikes that project from their surface, an unusually large RNA genome, and a …

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

M Hackbart, X Deng, SC Baker - Proceedings of the …, 2020 - National Acad Sciences
Coronaviruses (CoVs) are positive-sense RNA viruses that can emerge from endemic
reservoirs and infect zoonotically, causing significant morbidity and mortality. CoVs encode …