Emerging trends in the nanomedicine applications of functionalized magnetic nanoparticles as novel therapies for acute and chronic diseases
High-quality point-of-care is critical for timely decision of disease diagnosis and healthcare
management. In this regard, biosensors have revolutionized the field of rapid testing and …
management. In this regard, biosensors have revolutionized the field of rapid testing and …
The impact of chemical engineering and technological advances on managing diabetes: Present and future concepts
Monitoring blood glucose levels for diabetic patients is critical to achieve tight glycaemic
control. As none of the current antidiabetic treatments restore lost functional β-cell mass in …
control. As none of the current antidiabetic treatments restore lost functional β-cell mass in …
Principles and applications of magnetic nanomaterials in magnetically guided bioimaging
Imaging plays a pivotal role in the precise diagnosis of a variety of diseases. Various
imaging modalities have long secured their place in clinics. However, a lot of these …
imaging modalities have long secured their place in clinics. However, a lot of these …
[HTML][HTML] 3D in vivo magnetic particle imaging of human stem cell-derived islet organoid transplantation using a machine learning algorithm
Stem cell-derived islet organoids constitute a promising treatment of type 1 diabetes. A
major hurdle in the field is the lack of appropriate in vivo method to determine graft outcome …
major hurdle in the field is the lack of appropriate in vivo method to determine graft outcome …
Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis
Genetic studies have identified≥ 240 loci associated with the risk of type 2 diabetes (T2D),
yet most of these loci lie in non-coding regions, masking the underlying molecular …
yet most of these loci lie in non-coding regions, masking the underlying molecular …
Mouse models and human islet transplantation sites for intravital imaging
LE Wagner, O Melnyk, BE Duffett… - Frontiers in …, 2022 - frontiersin.org
Human islet transplantations into rodent models are an essential tool to aid in the
development and testing of islet and cellular-based therapies for diabetes prevention and …
development and testing of islet and cellular-based therapies for diabetes prevention and …
Artificial intelligence analysis of magnetic particle imaging for islet transplantation in a mouse model
Purpose Current approaches to quantification of magnetic particle imaging (MPI) for cell-
based therapy are thwarted by the lack of reliable, standardized methods of segmenting the …
based therapy are thwarted by the lack of reliable, standardized methods of segmenting the …
Particle-Based therapies for antigen specific treatment of type 1 diabetes
NR Lukesh, DD Middleton, EM Bachelder… - International journal of …, 2023 - Elsevier
Type 1 diabetes mellitus (T1D) is the leading metabolic disorder in children worldwide. Over
time, incidence rates have continued to rise with 20 million individuals affected globally by …
time, incidence rates have continued to rise with 20 million individuals affected globally by …
Delivery of therapeutic agents and cells to pancreatic islets: Towards a new era in the treatment of diabetes
Pancreatic islet cells, and in particular insulin-producing beta cells, are centrally involved in
the pathogenesis of diabetes mellitus. These cells are of paramount importance for the …
the pathogenesis of diabetes mellitus. These cells are of paramount importance for the …
Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice
S Erener, CE Ellis, A Ramzy, MM Glavas… - Cell Reports …, 2021 - cell.com
Summary miRNAs have crucial functions in many biological processes and are candidate
biomarkers of disease. Here, we show that miR-216a is a conserved, pancreas-specific …
biomarkers of disease. Here, we show that miR-216a is a conserved, pancreas-specific …