CD133: a stem cell biomarker and beyond

Z Li - Experimental hematology & oncology, 2013 - Springer
Cancer stem cells (CSCs) or tumor initiating cells (TICs) contribute to tumorigenesis,
metastasis, recurrence and chemoresistance. CD133, a pentaspan membrane glycoprotein …

Stem cells: A revolution in therapeutics—Recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies

M Mimeault, R Hauke, SK Batra - Clinical Pharmacology & …, 2007 - Wiley Online Library
Basic and clinical research accomplished during the last few years on embryonic, fetal,
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …

Combined Characterization of microRNA and mRNA Profiles Delineates Early Differentiation Pathways of CD133+ and CD34+ Hematopoietic Stem and Progenitor …

U Bissels, S Wild, S Tomiuk, M Hafner, H Scheel… - Stem …, 2011 - academic.oup.com
MicroRNAs (miRNAs) have been shown to play an important role in hematopoiesis. To
elucidate the role of miRNAs in the early steps of hematopoiesis, we directly compared …

Long-term human CD34+ stem cell-engrafted nonobese diabetic/SCID/IL-2Rγnull mice show impaired CD8+ T cell maintenance and a functional arrest of immature …

MC André, A Erbacher, C Gille… - The Journal of …, 2010 - journals.aai.org
Allogeneic hematopoietic stem cell transplantation represents the most effective form of
immunotherapy for chemorefractory diseases. However, animal models have been missing …

Current status and issues in cancer stem cell study

YM Yang, JW Chang - Cancer investigation, 2008 - Taylor & Francis
Cancer stem cells (CSCs) have been positively identified and successfully isolated from
some but not all cancers. The studies on CSCs to date suggest that these cells are rare …

Humoral activity of cord blood-derived stem/progenitor cells: implications for stem cell-based adjuvant therapy of neurodegenerative disorders

E Paczkowska, K Kaczyńska, E Pius-Sadowska… - PLoS …, 2013 - journals.plos.org
Background Stem/progenitor cells (SPCs) demonstrate neuro-regenerative potential that is
dependent upon their humoral activity by producing various trophic factors regulating cell …

NUP98 dysregulation in myeloid leukemogenesis

MAS Moore, KY Chung, M Plasilova… - Annals of the New …, 2007 - Wiley Online Library
Nucleoporin 98 (NUP98) is a component of the nuclear pore complex that facilitates mRNA
export from the nucleus. It is mapped to 11p15. 5 and is fused to a number of distinct …

Are globoseries glycosphingolipids SSEA-3 and-4 markers for stem cells derived from human umbilical cord blood?

H Suila, V Pitkänen, T Hirvonen… - Journal of molecular …, 2011 - academic.oup.com
Umbilical cord blood (UCB) is an efficient and valuable source of hematopoietic stem cells
(HSCs) for transplantation. In addition to HSCs it harbours low amounts of mesenchymal …

[HTML][HTML] N-glycan structures and associated gene expression reflect the characteristic N-glycosylation pattern of human hematopoietic stem and progenitor cells

H Hemmoranta, T Satomaa, M Blomqvist… - Experimental …, 2007 - Elsevier
OBJECTIVE: Cell surface glycans contribute to the adhesion capacity of cells and are
essential in cellular signal transduction. Yet, the glycosylation of hematopoietic stem and …

Early hematopoietic zinc finger protein—zinc finger protein 521: A candidate regulator of diverse immature cells

HM Bond, M Mesuraca, N Amodio, T Mega… - The international journal …, 2008 - Elsevier
The early hematopoietic zinc finger protein/zinc finger protein 521 (EHZF/ZNF521) is a
recently identified, 1131 amino-acid-long nuclear factor that contains 30 zinc fingers …