BDNF as a promising therapeutic agent in Parkinson's disease

E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

The neuroprotective effects of glucagon-like peptide 1 in Alzheimer's and Parkinson's disease: An in-depth review

N Reich, C Hölscher - Frontiers in neuroscience, 2022 - frontiersin.org
Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …

[HTML][HTML] Rational design of boron nitride with different dimensionalities for sustainable applications

N Han, S Wang, AK Rana, S Asif, JJ Klemeš… - … and Sustainable Energy …, 2022 - Elsevier
The application of boron nitride (BN) nanomaterials in various fields received extensive
attention in the past decades, attributed to its extraordinary characteristics: high surface …

Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy

TB Sampaio, AS Savall, MEZ Gutierrez… - Neural regeneration …, 2017 - journals.lww.com
Neurotrophic factors comprise essential secreted proteins that have several functions in
neural and non-neural tissues, mediating the development, survival and maintenance of …

Regulation of BDNF-TrkB signaling and potential therapeutic strategies for Parkinson's disease

W Jin - Journal of clinical medicine, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase
receptor type B (TrkB) are widely distributed in multiple regions of the human brain …

Brain-derived neurotrophic factor: a novel dynamically regulated therapeutic modulator in neurological disorders

V Sharma, TG Singh, A Kaur, A Mannan… - Neurochemical …, 2023 - Springer
The growth factor brain-derived neurotrophic factor (BDNF), and its receptor tropomyosin-
related kinase receptor type B (TrkB) play an active role in numerous areas of the adult …

NGF and BDNF in pediatrics syndromes

G Ferraguti, S Terracina, G Micangeli… - Neuroscience & …, 2023 - Elsevier
Neurotrophins (NTs) as nerve growth factor (NGF) and brain-derived neurotrophic factor
(BDNF) play multiple roles in different settings including neuronal development, function and …

Investigation of the molecular role of brain-derived neurotrophic factor in Alzheimer's disease

P Girotra, T Behl, A Sehgal, S Singh… - Journal of Molecular …, 2022 - Springer
Brain-derived neurotrophic factor (BDNF), or abrineurin, is a member of the neurotrophin
family of growth factors that acts on both the central and peripheral nervous systems. BDNF …

Gastrodia elata Blume (Tianma): Hope for Brain Aging and Dementia

K Heese - Evidence‐Based Complementary and Alternative …, 2020 - Wiley Online Library
Since aging‐related diseases, including dementia, represent major public health threats to
our society, physician‐scientists must develop innovative, interdisciplinary strategies to open …

Neurotrophic factor-based pharmacological approaches in neurological disorders

M Alfonsetti, M d'Angelo, V Castelli - Neural regeneration …, 2023 - journals.lww.com
Aging is a physiological event dependent on multiple pathways that are linked to lifespan
and processes leading to cognitive decline. This process represents the major risk factor for …