[HTML][HTML] Compounds Inhibiting Noppera-bo, a Glutathione S-transferase Involved in Insect Ecdysteroid Biosynthesis: Novel Insect Growth Regulators

K Ebihara, R Niwa - Biomolecules, 2023 - mdpi.com
Glutathione S-transferases (GSTs) are conserved in a wide range of organisms, including
insects. In 2014, an epsilon GST, known as Noppera-bo (Nobo), was shown to regulate the …

[HTML][HTML] Biological Activities of Ceratonia siliqua Pod and Seed Extracts: A Comparative Analysis of Two Cretan Cultivars

DA Kavvoura, MK Stefanakis, D Kletsas… - International Journal of …, 2023 - mdpi.com
Ceratonia siliqua L., commonly known as the carob tree, appears in most Mediterranean
countries, often cultivated for the collection of its fruits to be used as food for humans and …

[HTML][HTML] A new triphenylphosphonium-conjugated amphipathic cationic peptide with improved cell-penetrating and ROS-targeting properties

RA Ishkaeva, DV Salakhieva, R Garifullin… - Current Research in …, 2023 - Elsevier
We study for the first time whether triphenylphosphonium (TPP) moiety can improve cellular
delivery and redox properties of amphipathic cationic peptides based on YRFK/YrFK cell …

[HTML][HTML] Metal-chelating self-assembling peptide nanofiber scaffolds for modulation of neuronal cell behavior

K Dayob, A Zengin, R Garifullin, MO Guler, TI Abdullin… - Micromachines, 2023 - mdpi.com
Synthetic peptides are promising structural and functional components of bioactive and
tissue-engineering scaffolds. Here, we demonstrate the design of self-assembling nanofiber …

[HTML][HTML] How predicted temperature and salinity changes will modulate the impacts induced by terbium in bivalves?

M Andrade, J Pinto, AMVM Soares, M Solé, E Pereira… - Chemosphere, 2024 - Elsevier
The threat of climate change, which includes shifts in salinity and temperature, has
generated a global concern for marine organisms. These changes directly impact them and …

Evaluation of GHK peptide–heparin interactions in multifunctional liposomal covering

V Nikolaeva, M Kamalov, TI Abdullin… - Journal of Liposome …, 2024 - Taylor & Francis
Small biospecific peptides with defined chemical structure and cellular responses are
promising alternatives to full-length therapeutic proteins. Identification of these peptides …

[HTML][HTML] Design and Synthesis of Novel Antioxidant 2-Substituted-5, 7, 8-Trimethyl-1, 4-Benzoxazine Hybrids: Effects on Young and Senescent Fibroblasts

T Fotopoulou, A Papadopoulou, A Tzani, M Mamais… - Antioxidants, 2024 - mdpi.com
The exponential growth of the aged population worldwide is followed by an increase in the
prevalence of age-related disorders. Oxidative stress plays central role in damage …

[HTML][HTML] Characterization of Glutathione Dithiophosphates as Long-Acting H2S Donors

RA Ishkaeva, NN Khaertdinov, AV Yakovlev… - International Journal of …, 2023 - mdpi.com
Considering the important cytoprotective and signaling roles but relatively narrow
therapeutic index of hydrogen sulfide (H2S), advanced H2S donors are required to achieve …

ATP-hydrolyzing, DNA-damaging and cytotoxic activities of peptide-targeted cobalt (III) complex with diethylentriamine

MI Kamalov, AV Nemtarev, RA Ishkaeva… - Medicinal Chemistry …, 2024 - Springer
Coordination complexes of cobalt represent a potential alternative to anticancer platinum-
derived drugs owing to multiple activities and better toxicity profile. This work is aimed at …

Rapid Quantification of Oxidized and Reduced Forms of Glutathione Using Ortho -phthalaldehyde in Cultured Mammalian Cells In Vitro

C McBeth, D Brown, P Pokorski, L Lei… - JoVE (Journal of Visualized …, 2024 - jove.com
Glutathione has long been considered a key biomarker for determining the antioxidant
response of the cell. Hence, it is a primary marker for reactive oxygen species studies. The …