Advances in gelatin bioinks to optimize bioprinted cell functions
Gelatin is a widely utilized bioprinting biomaterial due to its cell‐adhesive and enzymatically
cleavable properties, which improve cell adhesion and growth. Gelatin is often covalently …
cleavable properties, which improve cell adhesion and growth. Gelatin is often covalently …
Extracellular matrix mechanobiology in cancer cell migration
The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …
chemically stimulating tumor cells, it also offers physical support that orchestrates the …
Multifunctional silk fibroin methacryloyl microneedle for diabetic wound healing
G Guan, Q Zhang, Z Jiang, J Liu, J Wan, P Jin, Q Lv - Small, 2022 - Wiley Online Library
Diabetic wound is one of the common complications in diabetic patients, which exhibits
chronic, hard‐to‐heal characteristics. The healing process of wounds is impaired by several …
chronic, hard‐to‐heal characteristics. The healing process of wounds is impaired by several …
Digital Light Processing 3D Bioprinting of Gelatin‐Norbornene Hydrogel for Enhanced Vascularization
Digital light processing (DLP) bioprinting can be used to fabricate volumetric scaffolds with
intricate internal structures, such as perfusable vascular channels. The successful …
intricate internal structures, such as perfusable vascular channels. The successful …
[HTML][HTML] Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions
The tumor microenvironment (TME) is known to direct cancer cell growth, migration, invasion
into the matrix and distant tissues, and to confer drug resistance in cancer cells. While …
into the matrix and distant tissues, and to confer drug resistance in cancer cells. While …
Dual functionalization of gelatin for orthogonal and dynamic hydrogel cross-linking
Gelatin-based hydrogels are widely used in biomedical fields because of their abundance of
bioactive motifs that support cell adhesion and matrix remodeling. Although inherently …
bioactive motifs that support cell adhesion and matrix remodeling. Although inherently …
Viscoelastic stiffening of gelatin hydrogels for dynamic culture of pancreatic cancer spheroids
The tumor microenvironment (TME) in pancreatic adenocarcinoma (PDAC) is a complex
milieu of cellular and non-cellular components. Pancreatic cancer cells (PCC) and cancer …
milieu of cellular and non-cellular components. Pancreatic cancer cells (PCC) and cancer …
Exploring New Dimensions of Tumor Heterogeneity: The Application of Single Cell Analysis to Organoid‐Based 3D In Vitro Models
N Landon‐Brace, NT Li… - Advanced Healthcare …, 2023 - Wiley Online Library
Modeling the heterogeneity of the tumor microenvironment (TME) in vitro is essential to
investigating fundamental cancer biology and developing novel treatment strategies that …
investigating fundamental cancer biology and developing novel treatment strategies that …
[HTML][HTML] Recent updates in click and computational chemistry for drug discovery and development
JH Cai, XZ Zhu, PY Guo, P Rose, XT Liu, X Liu… - Frontiers in …, 2023 - frontiersin.org
Drug discovery is a costly and time-consuming process with a very high failure rate.
Recently, click chemistry and computer-aided drug design (CADD) represent popular areas …
Recently, click chemistry and computer-aided drug design (CADD) represent popular areas …
[HTML][HTML] Enhancing anti-tumor potential: low-intensity vibration suppresses osteosarcoma progression and augments MSCs' tumor-suppressive abilities
Abstract Rationale: Osteosarcoma (OS), a common malignant bone tumor, calls for the
investigation of novel treatment strategies. Low-intensity vibration (LIV) presents itself as a …
investigation of novel treatment strategies. Low-intensity vibration (LIV) presents itself as a …