An overview of autism spectrum disorder, heterogeneity and treatment options

A Masi, MM DeMayo, N Glozier, AJ Guastella - Neuroscience bulletin, 2017 - Springer
Since the documented observations of Kanner in 1943, there has been great debate about
the diagnoses, the sub-types, and the diagnostic threshold that relates to what is now known …

The influence of neuroinflammation in Autism Spectrum Disorder

SM Matta, EL Hill-Yardin, PJ Crack - Brain, behavior, and immunity, 2019 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised
by deficits in social communication and restricted or repetitive behaviours. The clinical …

Emerging roles for the gut microbiome in autism spectrum disorder

HE Vuong, EY Hsiao - Biological psychiatry, 2017 - Elsevier
Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder that affects one
in 45 children in the United States, with a similarly striking prevalence in countries around …

The role of the immune system in autism spectrum disorder

A Meltzer, J Van de Water - Neuropsychopharmacology, 2017 - nature.com
Autism is a neurodevelopmental disorder characterized by deficits in communication and
social skills as well as repetitive and stereotypical behaviors. While much effort has focused …

Oxidative stress and immune system dysfunction in autism spectrum disorders

L Pangrazzi, L Balasco, Y Bozzi - International journal of molecular …, 2020 - mdpi.com
Autism Spectrum Disorders (ASDs) represent a group of neurodevelopmental disorders
associated with social and behavioral impairments. Although dysfunctions in several …

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

ML Estes, AK McAllister - Nature Reviews Neuroscience, 2015 - nature.com
Increasing evidence points to a central role for immune dysregulation in autism spectrum
disorder (ASD). Several ASD risk genes encode components of the immune system and …

The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models

L Mapelli, T Soda, E D'Angelo, F Prestori - International journal of …, 2022 - mdpi.com
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …

Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis

A Masi, DS Quintana, N Glozier, AR Lloyd… - Molecular …, 2015 - nature.com
The role of non-diagnostic features in the pathophysiology of autism spectrum disorders
(ASDs) is unclear. Increasing evidence suggests immune system alterations in ASD may be …

Consensus paper: pathological role of the cerebellum in autism

SH Fatemi, KA Aldinger, P Ashwood, ML Bauman… - The Cerebellum, 2012 - Springer
There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current …

[HTML][HTML] Distinct microbiome-neuroimmune signatures correlate with functional abdominal pain in children with autism spectrum disorder

RA Luna, N Oezguen, M Balderas… - Cellular and molecular …, 2017 - Elsevier
Background & Aims Emerging data on the gut microbiome in autism spectrum disorder
(ASD) suggest that altered host–microbe interactions may contribute to disease symptoms …