Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

Do Ionic Liquids Exhibit the Required Characteristics to Dissolve, Extract, Stabilize, and Purify Proteins? Past-Present-Future Assessment

P Bharmoria, AA Tietze, D Mondal, TS Kang… - Chemical …, 2024 - ACS Publications
Proteins are highly labile molecules, thus requiring the presence of appropriate solvents and
excipients in their liquid milieu to keep their stability and biological activity. In this field, ionic …

Proteins in ionic liquids: Reactions, applications, and futures

A Schindl, ML Hagen, S Muzammal… - Frontiers in …, 2019 - frontiersin.org
Biopolymer processing and handling is greatly facilitated by the use of ionic liquids, given
the increased solubility, and in some cases, structural stability imparted to these molecules …

Use of ionic liquids in protein and DNA chemistry

SK Shukla, JP Mikkola - Frontiers in Chemistry, 2020 - frontiersin.org
Ionic liquids (ILs) have been receiving much attention as solvents in various areas of
biochemistry because of their various beneficial properties over the volatile solvents and ILs …

Room temperature ionic liquids meet biomolecules: a microscopic view of structure and dynamics

A Benedetto, P Ballone - ACS Sustainable Chemistry & …, 2016 - ACS Publications
Room temperature ionic liquids (RTILs) and biomolecules are both paradigmatic classes of
organic molecules, each consisting of a prodigious number of distinct chemical species …

Ionic liquids for regulating biocatalytic process: Achievements and perspectives

P Xu, S Liang, MH Zong, WY Lou - Biotechnology advances, 2021 - Elsevier
Biocatalysis has found enormous applications in sorts of fields as an alternative to chemical
catalysis. In the pursue of green and sustainable chemistry, ionic liquids (ILs) have been …

Recent advancements in the ionic liquid mediated lignin valorization for the production of renewable materials and value-added chemicals

R Radhakrishnan, P Patra, M Das, A Ghosh - Renewable and Sustainable …, 2021 - Elsevier
Lignin is the most abundant aromatic polymer available on earth and is a recalcitrant by-
product in the lignocellulose biomass-based industry. In recent times even though about 1 g …

Aqueous ionic liquids and their effects on protein structures: an overview on recent theoretical and experimental results

J Smiatek - Journal of Physics: Condensed Matter, 2017 - iopscience.iop.org
Ionic liquids (ILs) are used in a variety of technological and biological applications. Recent
experimental and simulation results reveal the influence of aqueous ionic liquids on the …

A green pathway for lignin valorization: Enzymatic lignin depolymerization in biocompatible ionic liquids and deep eutectic solvents

E Liu, MIV Mercado, F Segato, MR Wilkins - Enzyme and microbial …, 2024 - Elsevier
Lignin depolymerization, which enables the breakdown of a complex and heterogeneous
aromatic polymer into relatively uniform derivatives, serves as a critical process in …

How to engineer organic solvent resistant enzymes: Insights from combined molecular dynamics and directed evolution study

H Cui, THJ Stadtmüller, Q Jiang, KE Jaeger… - …, 2020 - Wiley Online Library
Expanding synthetic capabilities to routinely employ enzymes in organic solvents (OSs) is a
dream for protein engineers and synthetic chemists. Despite significant advances in the field …