[HTML][HTML] The molecular activity of cannabidiol in the regulation of Nrf2 system interacting with NF-κB pathway under oxidative stress
SA Ekiner, A Gęgotek, E Skrzydlewska - Redox Biology, 2022 - Elsevier
Cannabidiol (CBD), the major non-psychoactive phytocannabinoid of Cannabis sativa L., is
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …
PIKfyve, expressed by CD11c-positive cells, controls tumor immunity
Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such
as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other …
as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other …
HTLV-1 infection and pathogenesis: new insights from cellular and animal models
G Forlani, M Shallak, RS Accolla… - International Journal of …, 2021 - mdpi.com
Since the discovery of the human T-cell leukemia virus-1 (HTLV-1), cellular and animal
models have provided invaluable contributions in the knowledge of viral infection …
models have provided invaluable contributions in the knowledge of viral infection …
p62: Friend or Foe? Evidences for OncoJanus and NeuroJanus Roles
S Emanuele, M Lauricella, A D'Anneo, D Carlisi… - International journal of …, 2020 - mdpi.com
p62 is a versatile protein involved in the delicate balance between cell death and survival,
which is fundamental for cell fate decision in the context of both cancer and …
which is fundamental for cell fate decision in the context of both cancer and …
Interplay between ADP-ribosyltransferases and essential cell signaling pathways controls cellular responses
F Boehi, P Manetsch, MO Hottiger - Cell discovery, 2021 - nature.com
Signaling cascades provide integrative and interactive frameworks that allow the cell to
respond to signals from its environment and/or from within the cell itself. The dynamic …
respond to signals from its environment and/or from within the cell itself. The dynamic …
NF-κB and MicroRNA deregulation mediated by HTLV-1 tax and HBZ
S Fochi, V Ciminale, E Trabetti, U Bertazzoni… - Pathogens, 2019 - mdpi.com
The risk of developing adult T-cell leukemia/lymphoma (ATLL) in individuals infected with
human T-cell lymphotropic virus 1 (HTLV-1) is about 3–5%. The mechanisms by which the …
human T-cell lymphotropic virus 1 (HTLV-1) is about 3–5%. The mechanisms by which the …
Autophagy in human T-cell leukemia virus type 1 (HTLV-1) induced leukemia
N Ducasa, D Grasso, P Benencio… - Frontiers in …, 2021 - frontiersin.org
Viruses play an important role in the development of certain human cancers. They are
estimated to contribute 16% to all human cancers. Human T-cell leukemia virus type 1 …
estimated to contribute 16% to all human cancers. Human T-cell leukemia virus type 1 …
The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation
Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATLL), and the neurological disease HTLV-1-associated …
leukemia/lymphoma (ATLL), and the neurological disease HTLV-1-associated …
The ubiquitin sensor and adaptor protein P62 mediates signal transduction of a viral oncogenic pathway
L Wang, MEA Howell, A Sparks-Wallace, J Zhao… - Mbio, 2021 - Am Soc Microbiol
ABSTRACT The Epstein-Barr virus (EBV) protein LMP1 serves as a paradigm that engages
complicated ubiquitination-mediated mechanisms to activate multiple transcription factors …
complicated ubiquitination-mediated mechanisms to activate multiple transcription factors …