Diagnosis of human immunodeficiency virus infection

BS Parekh, CY Ou, PN Fonjungo… - Clinical microbiology …, 2018 - Am Soc Microbiol
SUMMARY HIV diagnostics have played a central role in the remarkable progress in
identifying, staging, initiating, and monitoring infected individuals on life-saving antiretroviral …

HIV-1 drug resistance genotyping in resource limited settings: current and future perspectives in sequencing technologies

S Manyana, L Gounder, M Pillay, J Manasa, K Naidoo… - Viruses, 2021 - mdpi.com
Affordable, sensitive, and scalable technologies are needed for monitoring antiretroviral
treatment (ART) success with the goal of eradicating HIV-1 infection. This review discusses …

Impact of pretreatment low-abundance HIV-1 drug resistance on virological failure after 1 year of antiretroviral therapy in China

M Li, C Song, J Hu, A Dong, R Kang… - Journal of …, 2023 - academic.oup.com
Objectives To assess the impact of pretreatment low-abundance HIV drug-resistant variants
(LA-DRVs) on virological outcomes among ART-naive HIV-1-infected Chinese people who …

HIV drug resistance mutations detection by next-generation sequencing during antiretroviral therapy interruption in China

M Li, S Liang, C Zhou, M Chen, S Liang, C Liu, Z Zuo… - Pathogens, 2021 - mdpi.com
Patients with antiretroviral therapy interruption have a high risk of virological failure when re-
initiating antiretroviral therapy (ART), especially those with HIV drug resistance. Next …

[PDF][PDF] The evolving landscape of HIV drug resistance diagnostics for expanding testing in resource-limited settings

SC Inzaule, RL Hamers, R Paredes, C Yang… - AIDS Rev, 2017 - researchgate.net
Global scale-up of antiretroviral treatment has dramatically changed the prospects of
HIV/AIDS disease, rendering life-long chronic care and treatment a reality for millions of HIV …

Long-range HIV genotyping using viral RNA and proviral DNA for analysis of HIV drug resistance and HIV clustering

V Novitsky, M Zahralban-Steele… - Journal of clinical …, 2015 - Am Soc Microbiol
The goal of the study was to improve the methodology of HIV genotyping for analysis of HIV
drug resistance and HIV clustering. Using the protocol of Gall et al.(A. Gall, B. Ferns, C …

Combatting global infectious diseases: a network effect of specimen referral systems

PN Fonjungo, GA Alemnji, Y Kebede… - Clinical Infectious …, 2017 - academic.oup.com
The recent Ebola virus outbreak in West Africa clearly demonstrated the critical role of
laboratory systems and networks in responding to epidemics. Because of the huge …

Phylodynamics and migration data help describe HIV transmission dynamics in internally displaced people who inject drugs in Ukraine

G Kovalenko, A Yakovleva, P Smyrnov… - PNAS …, 2023 - academic.oup.com
Internally displaced persons are often excluded from HIV molecular epidemiology
surveillance due to structural, behavioral, and social barriers in access to treatment. We test …

Utilization of dried blood spot specimens can expedite nationwide surveillance of HIV drug resistance in resource-limited settings

G Zhang, J DeVos, S Medina-Moreno, N Wagar… - PLoS …, 2018 - journals.plos.org
Introduction Surveillance of HIV drug resistance (HIVDR) is crucial to ensuring the continued
success of antiretroviral therapy (ART) programs. With the concern of reduced genotyping …

HIV diversity and drug resistance from plasma and non‐plasma analytes in a large treatment programme in western Kenya

R Kantor, A DeLong, M Balamane… - African Journal of …, 2014 - journals.lww.com
Introduction: Antiretroviral resistance leads to treatment failure and resistance transmission.
Resistance data in western Kenya are limited. Collection of non-plasma analytes may …