Multifaceted role of neuropilins in the immune system: potential targets for immunotherapy
Neuropilins (NRPs) are non-tyrosine kinase cell surface glycoproteins expressed in all
vertebrates and widely conserved across species. The two isoforms, such as neuropilin-1 …
vertebrates and widely conserved across species. The two isoforms, such as neuropilin-1 …
Sialylation of N-glycans: mechanism, cellular compartmentalization and function
GP Bhide, KJ Colley - Histochemistry and cell biology, 2017 - Springer
Sialylated N-glycans play essential roles in the immune system, pathogen recognition and
cancer. This review approaches the sialylation of N-glycans from three perspectives. The …
cancer. This review approaches the sialylation of N-glycans from three perspectives. The …
Sialylation is involved in cell fate decision during development, reprogramming and cancer progression
F Li, J Ding - Protein & cell, 2019 - academic.oup.com
Sialylation, or the covalent addition of sialic acid to the terminal end of glycoproteins, is a
biologically important modification that is involved in embryonic development …
biologically important modification that is involved in embryonic development …
[HTML][HTML] Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system
N Lannes, E Eppler, S Etemad, P Yotovski, L Filgueira - Oncotarget, 2017 - ncbi.nlm.nih.gov
Microglia cells are the unique residential macrophages of the central nervous system (CNS).
They have a special origin, as they derive from the embryonic yolk sac and enter the …
They have a special origin, as they derive from the embryonic yolk sac and enter the …
Sialometabolism in brain health and Alzheimer's disease
P Rawal, L Zhao - Frontiers in Neuroscience, 2021 - frontiersin.org
Sialic acids refer to a unique family of acidic sugars with a 9-carbon backbone that are
mostly found as terminal residues in glycan structures of glycoconjugates including both …
mostly found as terminal residues in glycan structures of glycoconjugates including both …
Polysialic acid is a cellular receptor for human adenovirus 52
A Lenman, AM Liaci, Y Liu… - Proceedings of the …, 2018 - National Acad Sciences
Human adenovirus 52 (HAdV-52) is one of only three known HAdVs equipped with both a
long and a short fiber protein. While the long fiber binds to the coxsackie and adenovirus …
long and a short fiber protein. While the long fiber binds to the coxsackie and adenovirus …
Sialylation acts as a checkpoint for innate immune responses in the central nervous system
Sialic acids are monosaccharides that normally terminate the glycan chains of cell surface
glyco‐proteins and‐lipids in mammals, and are highly enriched in the central nervous tissue …
glyco‐proteins and‐lipids in mammals, and are highly enriched in the central nervous tissue …
The versatile roles of ADAM8 in cancer cell migration, mechanics, and extracellular matrix remodeling
CT Mierke - Frontiers in cell and developmental biology, 2023 - frontiersin.org
The posttranslational proteolytic cleavage is a unique and irreversible process that governs
the function and half-life of numerous proteins. Thereby the role of the family of A disintegrin …
the function and half-life of numerous proteins. Thereby the role of the family of A disintegrin …
E-selectin in vascular pathophysiology
J Zhang, S Huang, Z Zhu, A Gatt, J Liu - Frontiers in immunology, 2024 - frontiersin.org
Selectins are a group of Ca2+-dependent, transmembrane type I glycoproteins which attract
cell adhesion and migration. E-selectin is exclusively expressed in endothelial cells, and its …
cell adhesion and migration. E-selectin is exclusively expressed in endothelial cells, and its …
ADAM8 expression in breast cancer derived brain metastases: functional implications on MMP‐9 expression and transendothelial migration in breast cancer cells
C Conrad, M Götte, U Schlomann… - … journal of cancer, 2018 - Wiley Online Library
Metastatic breast cancer affects long‐term survival and is a major cause of cancer death for
women worldwide. The Metalloprotease‐Disintegrin ADAM8 promotes breast cancer …
women worldwide. The Metalloprotease‐Disintegrin ADAM8 promotes breast cancer …