Mechanisms of melatonin in obesity: a review

Q Guan, Z Wang, J Cao, Y Dong, Y Chen - International journal of …, 2021 - mdpi.com
Obesity and its complications have become a prominent global public health problem that
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …

Effects of melatonin on liver injuries and diseases

JJ Zhang, X Meng, Y Li, Y Zhou, DP Xu, S Li… - International Journal of …, 2017 - mdpi.com
Liver injuries and diseases are serious health problems worldwide. Various factors, such as
chemical pollutants, drugs, and alcohol, could induce liver injuries. Liver diseases involve a …

Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota

W Ren, P Wang, J Yan, G Liu, B Zeng… - Journal of pineal …, 2018 - Wiley Online Library
Melatonin influences intestinal microbiota and the pathogenesis of various diseases. This
study was conducted to explore whether melatonin alleviates weanling stress through …

Ovariectomized rodents as a menopausal metabolic syndrome model. A minireview

JML Medina-Contreras, R Villalobos-Molina… - Molecular and Cellular …, 2020 - Springer
Bilateral ovariectomy is the best characterized and the most reported animal model of
human menopause. Ovariectomized rodents develop insulin resistance (IR) and visceral …

The interplay between metabolic dysregulations and non-alcoholic fatty liver disease in women after menopause

R Robeva, D Mladenović, M Vesković, D Hrnčić… - Maturitas, 2021 - Elsevier
The hypoestrogenic period after menopause and associated metabolic imbalance might
facilitate the onset of non-alcoholic fatty liver disease (NAFLD) and its progression. The …

Meta‐analysis and machine learning reveal the antiobesity effects of melatonin on obese rodents

Y Li, X Sun, M Wang, Y Jiang, QQ Ge, T Li… - Obesity …, 2024 - Wiley Online Library
Melatonin appears to be a promising supplement for obesity treatment. The antiobesity
effects of melatonin on obese rodents are influenced by various factors, including the …

Melatonin inhibits osteoclastogenesis and bone loss in ovariectomized mice by regulating PRMT1-mediated signaling

JH Choi, AR Jang, MJ Park, D Kim, JH Park - Endocrinology, 2021 - academic.oup.com
Melatonin, a pineal gland hormone, has been suggested to treat postmenopausal
osteoporosis due to its inhibitory effect on osteoclast differentiation. We previously reported …

N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via …

M Delgobo, JP Agnes, RM Goncalves… - The Journal of nutritional …, 2019 - Elsevier
Sexual hormone deficiency has been associated with metabolic changes, oxidative stress
and subclinical inflammation in postmenopausal women. Hormone replacement therapies …

The effects of antibiotics and melatonin on hepato-intestinal inflammation and gut microbial dysbiosis induced by a short-term high-fat diet consumption in rats

A Yildirim, SA Tamer, D Sahin, F Bagriacik… - British journal of …, 2019 - cambridge.org
High-fat diet (HFD) consumption leads to metabolic disorders, gastrointestinal dysfunction
and intestinal dysbiosis. Antibiotics also disrupt the composition of intestinal microbiota. The …

The effects of sinapic acid on the development of metabolic disorders induced by estrogen deficiency in rats

M Zych, I Kaczmarczyk-Sedlak… - Oxidative medicine …, 2018 - Wiley Online Library
Sinapic acid is a natural phenolic acid found in fruits, vegetables, and cereals, exerting
numerous pharmacological effects. The aim of the study was to investigate the influence of …