Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies
BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …
Metabolomics and proteomics in type 2 diabetes
ZZ Chen, RE Gerszten - Circulation research, 2020 - Am Heart Assoc
The persistent increase in the worldwide burden of type 2 diabetes mellitus (T2D) and the
accompanying rise of its complications, including cardiovascular disease, necessitates our …
accompanying rise of its complications, including cardiovascular disease, necessitates our …
Integrative modeling of quantitative plasma lipoprotein, metabolic, and amino acid data reveals a multiorgan pathological signature of SARS-CoV-2 infection
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection on human blood plasma were characterized using multiplatform metabolic …
infection on human blood plasma were characterized using multiplatform metabolic …
Metabolic architecture of acute exercise response in middle-aged adults in the community
M Nayor, RV Shah, PE Miller, JB Blodgett, M Tanguay… - Circulation, 2020 - Am Heart Assoc
Background: Whereas regular exercise is associated with lower risk of cardiovascular
disease and mortality, mechanisms of exercise-mediated health benefits remain less clear …
disease and mortality, mechanisms of exercise-mediated health benefits remain less clear …
[HTML][HTML] The plasma metabolome of long COVID patients two years after infection
Y López-Hernández, J Monárrez-Espino, DAG López… - Scientific reports, 2023 - nature.com
One of the major challenges currently faced by global health systems is the prolonged
COVID-19 syndrome (also known as “long COVID”) which has emerged as a consequence …
COVID-19 syndrome (also known as “long COVID”) which has emerged as a consequence …
[HTML][HTML] Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study
S Wang, M Li, H Lin, G Wang, Y Xu, X Zhao, C Hu… - Cell Reports …, 2022 - cell.com
Although previous studies suggest that amino acids (AAs) and microbiota-related
metabolites (MRMs) are associated with type 2 diabetes mellitus (T2DM), the results remain …
metabolites (MRMs) are associated with type 2 diabetes mellitus (T2DM), the results remain …
[HTML][HTML] Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts
Background Amino acid metabolism is dysregulated in colorectal cancer patients; however,
it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent …
it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent …
Dietary metabolic signatures and cardiometabolic risk
RV Shah, LM Steffen, M Nayor, JP Reis… - European heart …, 2023 - academic.oup.com
Aims Observational studies of diet in cardiometabolic-cardiovascular disease (CM-CVD)
focus on self-reported consumption of food or dietary pattern, with limited information on …
focus on self-reported consumption of food or dietary pattern, with limited information on …
[HTML][HTML] Metabolic perspective of astrocyte dysfunction in Alzheimer's disease and type 2 diabetes brains
Z Shen, ZY Li, MT Yu, KL Tan, S Chen - Biomedicine & pharmacotherapy, 2023 - Elsevier
The term type III diabetes (T3DM) has been proposed for Alzheimer's disease (AD) due to
the shared molecular and cellular features between type 2 diabetes (T2DM) and insulin …
the shared molecular and cellular features between type 2 diabetes (T2DM) and insulin …
[HTML][HTML] Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction
An integrative multi-modal metabolic phenotyping model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …